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Chemistry

Core chemical ideas, from atoms and reactions to organic compounds and biochemistry.

For: Learners at different starting points, from curious beginners to students reviewing core concepts.

After this page you can: Choose a learning path and explain a chemical structure, reaction, or molecular process using core concepts.

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Part of: Science

About Chemistry

Chemistry studies the composition, structure, and properties of matter, and how different forms of matter can be interconverted. Its branches include organic chemistry, which focuses on carbon-containing compounds, and biochemistry, which examines the chemical basis of living things.

A useful way to study chemistry is to connect what substances are made of with how their structures, properties, and reactions relate. MIT’s introductory course organizes its material into five units. Start with the foundations, then follow a route into organic chemistry or biochemistry.

Start here

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I’m reviewing core chemistry

Use MIT’s independent-study course to revisit the central topics in an organized sequence.

Start with: Principles of Chemical Science

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I want to connect chemistry with living things

Use MIT’s course materials to explore the chemistry of cells and their building blocks.

Start with: Biological Chemistry I

Learn the foundations

1.Atoms, elements, and molecular structureChemical formulas and structural models describe the atoms in a substance and how they are arranged.

Chemical formulas and structural models describe the atoms in a substance and how they are arranged. These foundations connect the identity of elements to the structures and properties of molecules.

Atom

The smallest particle of an element that retains that element’s identity in chemical combinations.

Isotope

An atom of an element with the same atomic number as other atoms of that element but a different mass number.

Try it

A neutral atom has 6 protons and 6 neutrons. What is its atomic number and mass number?

Its atomic number is 6, and its mass number is 12.

2.Chemical reactions and reaction pathwaysA balanced equation shows the reactants and products, while a reaction mechanism describes the sequence of steps by which a reaction occurs.

A balanced equation shows the reactants and products, while a reaction mechanism describes the sequence of steps by which a reaction occurs. Studying reactions links chemical formulas to changes in bonding and to measurable rates.

Reaction mechanism

A step-by-step description of how a chemical reaction occurs.

Intermediate

A species formed in one reaction step and consumed in a later step.

Try it

Add these steps and cancel any species that appears on both sides: A → B; B → C.

The overall reaction is A → C; B is an intermediate because it is produced and then consumed.

3.Energy, equilibrium, and reaction ratesThermodynamics and chemical equilibrium describe how energy and conditions relate to chemical systems.

Thermodynamics and chemical equilibrium describe how energy and conditions relate to chemical systems. Kinetics focuses on reaction rates, which collision theory connects to the frequency, orientation, and energy of molecular collisions.

Activation energy

The minimum energy needed for reactants to form products during a collision.

Redox reaction

A reaction involving changes in oxidation states; some redox reactions transfer electrons between reactant species.

Try it

According to collision theory, name two conditions that help a collision between reactants lead to products.

The reactants must collide with a suitable orientation and sufficient energy.

4.Organic chemistry and biochemistryOrganic chemistry examines carbon-containing compounds, including hydrocarbons whose carbon atoms can form chains and rings.

Organic chemistry examines carbon-containing compounds, including hydrocarbons whose carbon atoms can form chains and rings. Biochemistry applies chemical ideas to living systems, including biological macromolecules and the reactions that build or break them down.

Hydrocarbon

An organic compound containing only carbon and hydrogen.

Monomer

A molecular subunit that can combine with other subunits to form a larger molecule such as a polymer.

Try it

A molecule contains only carbon and hydrogen. What class of organic compound does it belong to?

It is a hydrocarbon.

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Books

Glossary

Every free Chemistry course and book on RedLectern

Free Chemistry online courses

  1. Advanced Organic ChemistryMIT 5.43 · Browse materials
  2. Atmospheric ChemistryMIT 1.84J · Browse materials
  3. Atmospheric Physics and ChemistryMIT 10.571J · Browse materials
  4. Biological Chemistry IMIT 5.07SC · Browse materials · Video
  5. Biological Chemistry IIMIT 5.08J · Browse materials · Video
  6. Biological Engineering DesignMIT 20.380J · Browse materials
  7. Chemistry Behind the Magic: Chemical Demonstrations for the ClassroomMIT RES.HS-002 · Browse materials · Video
  8. Chemistry of SportsMIT ES.010 · Browse materials · Video
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  1. ChemLab Boot CampMIT RES.HS-003 · Browse materials · Video
  2. Climate Physics and ChemistryMIT 12.842 · Browse materials
  3. Computational Quantum Mechanics of Molecular and Extended SystemsMIT 10.675J · Browse materials
  4. Crystal Structure AnalysisMIT 5.069 · Browse materials
  5. Crystal Structure RefinementMIT 5.067 · Browse materials
  6. Digital Lab Techniques ManualMIT RES.5-0001 · Browse materials · Video
  7. Introduction to Organic Synthesis LaboratoryMIT 5.37 · Browse materials
  8. Introduction to Solid State ChemistryMIT 3.091SC · Browse materials · Video
  9. Introduction to Solid-State ChemistryMIT 3.091 · Browse materials · Video
  10. Introductory Quantum Mechanics IMIT 5.73 · Browse materials
  11. Introductory Quantum Mechanics IIMIT 5.74 · Browse materials · Video
  12. Introductory Quantum Mechanics IIMIT 5.74 · Browse materials · Video
  13. Laboratory ChemistryMIT 5.310 · Browse materials · Video
  14. Marine ChemistryMIT 12.742 · Browse materials · Video
  15. Non-Equilibrium Statistical MechanicsMIT 5.72 · Browse materials
  16. Organic Chemistry IMIT 5.12 · Browse materials
  17. Organic Chemistry IMIT 5.12 · Browse materials
  18. Organic Chemistry IIMIT 5.13 · Browse materials
  19. Physical ChemistryMIT 5.61 · Browse materials · Video
  20. Physical Chemistry IIMIT 5.62 · Browse materials
  21. Physics and Chemistry of the Terrestrial PlanetsMIT 12.002 · Browse materials
  22. Principles of Chemical ScienceMIT 5.111 · Browse materials · Video
  23. Principles of Chemical ScienceMIT 5.111SC · Browse materials · Video
  24. Principles of Chemical ScienceMIT 5.112 · Browse materials · Video
  25. Principles of Inorganic Chemistry IIIMIT 5.05 · Browse materials
  26. Protein Folding and Human DiseaseMIT 7.88J · Browse materials
  27. Quantum Mechanics IMIT 5.73 · Browse materials
  28. Small-Molecule Spectroscopy and DynamicsMIT 5.80 · Browse materials · Video
  29. Synthetic Organic Chemistry IIMIT 5.512 · Browse materials
  30. Teaching College-Level Science and EngineeringMIT 5.95J · Browse materials · Video
  31. Thermodynamics & KineticsMIT 5.60 · Browse materials · Video
  32. Thermodynamics of Biomolecular SystemsMIT 20.110J · Browse materials

40 of 51 shown. Search the Catalog for Chemistry →

How these courses are chosen

Listed as Chemistry courses:

  • those whose department’s name includes “Chemistry”, or
  • those whose title contains “Chemistry”, or
  • those tagged “Chemistry” as one of at most 2 topic tags, or as the first of 3.

Free Chemistry textbooks and books

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Search all 114 Chemistry books on the Books page →

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