MIT OpenCourseWare

Browse materialsMIT 20.110J · Fall 2005

Thermodynamics of Biomolecular Systems

Subjects: Chemistry · Mechanical Engineering

Art: Robert Hooke, Micrographia Scheme 07, 1665 · Public domain

Instructors: Prof. Kim Hamad-Schifferli, Prof. Linda Griffith, Prof. Moungi Bawendi, Prof. Robert Field
Term: Fall 2005
Level: Undergraduate
What's inside: 1 lecture note · 1 reading · 52 other files · 4 web pages
Materials open: MIT OCW

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About this course

Source: MIT OpenCourseWare 20.110J Thermodynamics of Biomolecular Systems, Fall 2005, Prof. Kim Hamad-Schifferli, Prof. Linda Griffith, Prof. Moungi Bawendi, Prof. Robert Field — original course page on ocw.mit.edu ↗. License: CC BY-NC-SA 4.0. Study order: MIT's own listing order, section by section. Taken from MIT's published course files, downloaded from ocw.mit.edu on September 23, 2026. How RedLectern is built.

Materials are grouped the way MIT organized them. A verified, course-wide order has not been established here.

Before you start

Prerequisites are not listed here. Check MIT's own syllabus for this course.

How this course was organized

What's here, and what isn't

A lecture sequence of 36 items is confirmed. No assignments or exams were found for this course, so it stays as organized materials rather than a full course order.

Materials by section

Grouped by section, as MIT organized them. Not sequenced or ordered.

Lecture Notes

29 files

Recitations

7 files

Other materials from this course

16 files

MIT OpenCourseWare, Prof. Kim Hamad-Schifferli, Prof. Linda Griffith, Prof. Moungi Bawendi, Prof. Robert Field, 20.110J Thermodynamics of Biomolecular Systems, Fall 2005.

License: CC BY-NC-SA 4.0 · Edition: Fall 2005 · Open the original course on OCW ↗

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Thermodynamics of Biomolecular Systems

Before you start

What's here, and what isn't

Materials by section

Lecture Notes

Recitations

Other materials from this course

Lecture 1: Introduction to Thermo; 0th Law; Temperature; Work; Heat

Lecture 2: State Functions, 1st Law, Paths

Lecture 3: Joule and Joule-Thompson; Heat Capacity

Lecture 4: Reversible and Irreversible Processes

Lecture 5: Thermochemistry

Lecture 6: 2ⁿd Law; Entropy (Boltzmann and Clausius)

Lecture 7: ΔS for Reversible and Irreversible Processes

Lecture 8: Equilibrium; Maxwell Relations; Free Energy

Lecture 9: Chemical Potential; Phase Equilibrium

Lecture 10: Chemical Equilibrium; Equilibrium Constant

Lecture 11: Standard States; Gibbs-Duhem

Lecture 12: ΔG⁰= -RTlnK; Example

Lecture 13: Boltzmann Distribution

Lecture 14: Thermo and Boltzmann Distribution

Lecture 15: Occupation of States

Lecture 16: Third Law

Lecture 17: Phase Equilibria, Single Component

Lecture 18: Phase Equilibria II; Clausius Clapeyron

Lecture 19: Regular Solutions; Mixing Energy; Mean Fields

Lecture 20: Nonideal Solutions

Lecture 21: Solvation; Colligative Properties

Lecture 22: Osmotic Pressure and Phase Partitioning

Lecture 23: Surface Tension

Lecture 24: Polymer 1 - Freely Jointed Chain

Lecture 25: Polymer 2 - Chain Conformation

Lecture 26: Polymer 3 - Rubber Elasticity

Lecture 27: Electrolyte Solutions

Lecture 28: Electrolytes at Interfaces; Debye Length

Lecture 29: Titration of Polyelectrolytes

Lecture 30: Thermodynamics of DNA Hybridization

Lecture 31: Cooperativity

Lecture 32: Cooperativity, Part 2

Lecture 33: Cooperativity, Part 3

Lecture 34: Driving Forces for Self-Assembly

Lecture 35: Special Topic (Coarse Grain/Monte Carlo Model)

Lecture 36: Course Review and Evaluations