Instructor Insights · Videos
MIT OpenCourseWare
Biological Chemistry I
- Instructors
- Prof. John Essigmann, Prof. Joanne Stubbe, Dr. Bogdan Fedeles
- Term
- Fall 2013
- Level
- Undergraduate
- What's inside
- 78 videos · 10 problem sets · 4 exams · 10 solutions · 107 other files · 31 web pages
- Materials open
- Videos here · files on MIT OCW
About this course
Source: MIT OpenCourseWare 5.07SC Biological Chemistry I, Fall 2013, Prof. John Essigmann, Prof. Joanne Stubbe, Dr. Bogdan Fedeles — original course page on ocw.mit.edu ↗. License: CC BY-NC-SA 4.0. Study order: MIT's own listing order, section by section. Taken from MIT's published course files, downloaded from ocw.mit.edu on September 23, 2026. How RedLectern is built.
Materials are grouped the way MIT organized them. A verified, course-wide order has not been established here.
Learn one topic
11 concept pages, one per MIT session: the clips, notes and practice for that topic. MIT solutions for 3 of 11 topics.
All 11 topics
- What is Biochemistry? MIT solutions
- Enzyme Kinetics and Enzyme Inhibition MIT solutions
- Biochemical Transformations III MIT solutions
- Glycolysis and Early Stages of Respiration
- Maintenance of Redox Neutrality
- Respiration: Proton Pumps and ATP Synthesis
- Lipid Catabolism: Fatty Acid Beta-Oxidation
- Fatty Acid and Lipid Biosynthesis
- Carbohydrate Biosynthesis I: Glycogen Synthesis
- Carbohydrate Biosynthesis III: Pentose Phosphate Pathway
- Regulation of Metabolism
Before you start
Prerequisites are not listed here. Check MIT's own syllabus for this course.
How this course was organized
What's here, and what isn't
- This course has 43 videos, each embedded on its own MIT page, across 13 sections. They're shown in MIT's listing order within each section. A verified course-wide order is not claimed for this course.
Not included here
15 items from the source could not be safely included:
- MIT's page format for this item wasn't recognized clearly enough to place it safely. (12 items)
- Referenced in a table, but without MIT's own verified order, so it isn't used to claim a sequence. (3 items)
Materials by section
Grouped by section, as MIT organized them. Not sequenced or ordered.
Lexicon
- Lexicon of Biochemical Reactions: Cofactors Formed from Vitamin B12 Open ↗
- Lexicon of Biochemical Reactions: Vitamin B6 / PLP Open ↗
- Lexicon of Biochemical Reactions: Introduction Open ↗
- Lexicon of Biochemical Reactions: Redox Cofactors Open ↗
Module I: Basic Biochemistry
22 items in this section
Session 1
- Session 1: Problem Set 1 Download
- Session 1: Problem Set 1 Solutions Download
- Session 1: What is Biochemistry? Download
Session 2
- Session 2: Introduction to Protein Structure and Function Download
- Session 2: Protein Structure and Function Continued Download
Session 3
- Session 3: Enzymes and Catalysis Open ↗
- Session 3: Enzymes and Catalysis Download
- Session 3: Problem Set 2 Download
- Session 3: Problem Set 2 Solutions Download
- Session 3: Problem Set 2, Problem 1: Primary Structure Open ↗
Session 4
- Session 4: Enzymes Kinetics and Enzyme Inhibition Download
- Session 4: Problem Set 3 Download
- Session 4: Problem Set 3 Solutions Download
Session 5
- Session 5: Biochemical Transformations I Download
- Session 5: Problem Set 4 Download
- Session 5: Problem Set 4 Solutions Download
- Session 5: Problem Set 4, Problem 2: The Mechanism of HMG-CoA Synthase Open ↗
- Carbonyl Chemistry Open ↗
Session 6
Session 7
Module II: Production of Energy in the Cell
38 items in this section
- Problem Set 7, Problem 1: Tracing Labels through Pathways Open ↗
- Session 11: PLP (Pyridoxal Phosphate) Reactions Open ↗
Session 8
7 files
- Session 8: Abbreviations List Download
- Session 8: Introduction to Sugar Chemistry Download
- Session 8: Metabolic Chart Download
- Session 8: Metabolism and Carbohydrate Catabolism Storyboard Download
- Session 8: Overview of Glycolysis Download
- Session 8: Problem Set 6 Download
- Session 8: Problem Set 6 Solutions Download
- Session 8: Intro to Sugar Chemistry and Carbohydrate Catabolism Open ↗
- Session 8: Problem Set 6, Problem 2: Mechanism of Phosphoglycerate Mutase Open ↗
Session 9
- Session 9: Carbohydrate Catabolism Download
- Session 9: Endings to Glycolysis Download
- Session 9: Pyruvate Dehydrogenase Slides Download
Session 10
- Session 10: Problem Set 7 Download
- Session 10: Problem Set 7 Solutions Download
- Session 10: Problem Set 7, Problem 1: Tracing Labels through Pathways Open ↗
- Session 10: Respiration: TCA Cycle Open ↗
- Session 10: TCA Cycle Storyboard Download
Session 11
Session 12
- Session 12: PLP (Pyridoxal Phosphate) Chemistry Open ↗
- Session 12: Problem Set 8 Download
- Session 12: Problem Set 8 Solutions Download
- Session 12: Problem Set 8, Question 2: Bioenergetics of the Electron Transport Chain Open ↗
- Session 12: Respiration: ETOP Open ↗
- Session 12: Stages of Respiration Storyboard Download
Session 13
Session 14
Session 15
- Session 15: Chemical Interlude Storyboard Download
- Session 15: Problem Set 9 Download
- Session 15: Problem Set 9 Solutions Download
- Session 15: Problem Set 9, Problem 1: Catabolism of Triacylglycerols Open ↗
- Session 15: Special Cases in Fatty Acid Metabolism Open ↗
Session 16
Module III: Using Energy to Make Macromolecules
9 items in this section
Session 17
Session 18
Session 19
- Session 19: Carbohydrate Biosynthesis II: Gluconeogenesis Open ↗
- Session 19: Gluconeogensis Storyboard Download
- Session 19: Problem Set 10 Download
- Session 19: Problem Set 10 Solutions Download
- Session 19: Problem Set 10, Problem 3: Gluconeogenesis Open ↗
Session 20
Session 21
Resource Index
9 videos
- Problem Set 2, Problem 1: Primary Structure Open ↗
- Problem Set 4, Problem 2: The Mechanism of HMG-CoA Synthase Open ↗
- Problem Set 6, Problem 2: Mechanism of Phosphoglycerate Mutase Open ↗
- Problem Set 7, Problem 1: Tracing Labels through Pathways Open ↗
- Problem Set 8, Question 2: Bioenergetics of the Electron Transport Chain Open ↗
- Problem Set 9, Problem 1: Catabolism of Triacylglycerols Open ↗
- Problem Set 10, Problem 3: Gluconeogenesis Open ↗
- Ses 12: Respiration: ETOP Open ↗
- Session 18: Carbohydrate Biosynthesis I: Glycogen Synthesis Open ↗
Other materials from this course
78 video transcripts
- Transcript for Session 11: PLP (Pyridoxal Phosphate) Reactions Download
- Transcript for Lexicon of Biochemical Reactions: Cofactors Formed from Vitamin B12 Download
- Transcript for Lexicon of Biochemical Reactions: Introduction Download
- Transcript for Session 17: Fatty Acid and Lipid Biosynthesis Download
- Transcript for Session 10: Problem Set 7, Problem 1: Tracing Labels through Pathways Download
- Transcript for Research Focus: Ribonucleotide Reductases (RNRs) Download
- Transcript for Session 8: Problem Set 6, Problem 2: Mechanism of Phosphoglycerate Mutase Download
- Transcript for Session 16: Ketogenesis, Diabetes and Starvation Download
- Transcript for Lexicon of Biochemical Reactions: Vitamin B6 / PLP Download
- Transcript for Problem Set 4, Problem 2: The Mechanism of HMG-CoA Synthase Download
- Transcript for Session 15: Special Cases in Fatty Acid Metabolism Download
- Transcript for Session 5: Carbonyl Chemistry Download
- Transcript for Session 12: PLP (Pyridoxal Phosphate) Chemistry Download
- Transcript for Problem Set 8, Question 2: Bioenergetics of the Electron Transport Chain Download
- Transcript for Session 3: Enzymes and Catalysis Download
- Transcript for Teaching Central Pathways to Help Students Understand Metabolism Download
- Transcript for Problem Set 5, Problem 5: How Mannose, an Isomer of Glucose, Enters Glycolysis Download
- Transcript for Session 20: Carbohydrate Biosynthesis III: Pentose Phosphate Pathway Download
- Transcript for PLP (Pyridoxal Phosphate) Chemistry Download
- Transcript for Session 21: Regulation of Metabolism Download
- Transcript for Problem Set 3, Question 2: Proteases: Mechanisms of Inhibition Download
- Transcript for Becoming a Toxicologist Download
- Transcript for Problem Set 10, Problem 3: Gluconeogenesis Download
- Transcript for ses19: Carbohydrate Biosynthesis II: Gluconeogenesis Download
- Transcript for Session 14: Lipid Catabolism: Fatty Acid Beta-Oxidation Download
- Transcript for Advice for Next Teaching Generation: Focus Curricula on the Microbial World Download
- Transcript for Lexicon of Biochemical Reactions: Cofactors Formed from Vitamin B12 Download
- Transcript for Problem Set 8, Question 2: Bioenergetics of the Electron Transport Chain Download
- Transcript for Why Students Should Memorize Amino Acid Side Chains Download
- Transcript for Session 18: Carbohydrate Biosynthesis I: Glycogen Synthesis Download
- Transcript for ses 9: Glycolysis and Early Stages of Respiration Download
- Transcript for Session 10: Respiration: TCA Cycle Download
- Transcript for Lexicon of Biochemical Reactions: Introduction Download
- Transcript for ses 10: Respiration: TCA Cycle Download
- Transcript for Session 16: Ketogenesis, Diabetes and Starvation Download
- Transcript for Lexicon of Biochemical Reactions: Redox Cofactors Download
- Transcript for Ses 17: Fatty Acid and Lipid Biosynthesis Download
- Transcript for Session 16: The Science Behind Type II Diabetes Download
- Transcript for ses21: Regulation of Metabolism Download
- Transcript for Session 11: Maintenance of Redox Neutrality Download
- Transcript for Problem Set 1, Problem 1: Sizes and Equilibria Download
- Transcript for Ses 13: Respiration: Proton Pumps and ATP Synthesis Download
- Transcript for Lecture 5: Enzymes and Catalysis Download
- Transcript for Problem Set 7, Problem 1: Tracing Labels through Pathways Download
- Transcript for Session 5: Problem Set 4, Problem 2: The Mechanism of HMG-CoA Synthase Download
- Transcript for Problem Set 6, Problem 2: Mechanism of Phosphoglycerate Mutase Download
- Transcript for Using a Vitamin Bottle as a Teaching Tool Download
- Transcript for Session 8: Intro to Sugar Chemistry and Carbohydrate Catabolism Download
- Transcript for Ses 11: Maintenance of Redox Neutrality Download
- Transcript for Session 9: Glycolysis and Early Stages of Respiration Download
- Transcript for ses 8: Intro to Sugar Chemistry and Carbohydrate Catabolism Download
- Transcript for Problem Set 9, Problem 1: Catabolism of Triacylglycerols Download
- Transcript for Ses 15: Special Cases in Fatty Acid Metabolism Download
- Transcript for Lexicon of Biochemical Reactions: Redox Cofactors Download
- Transcript for Carbonyl Chemistry Download
- Transcript for Session 7: Problem Set 5, Problem 5: How Mannose, an Isomer of Glucose, Enters Glycolysis Download
- Transcript for Problem Set 2, Problem 1: Primary Structure Download
- Transcript for How Can You Not Think Enzymes Are Cool? Download
- Transcript for Session 18: Carbohydrate Biosynthesis I: Glycogen Synthesis Download
- Transcript for Session 3: Problem Set 2, Problem 1: Primary Structure Download
- Transcript for Session 15: Problem Set 9, Problem 1: Catabolism of Triacylglycerols Download
- Transcript for Session 12: Problem Set 8, Question 2: Bioenergetics of the Electron Transport Chain Download
- Transcript for Session 19: Carbohydrate Biosynthesis II: Gluconeogenesis Download
- Transcript for Focusing on the Morphological Unit of Life Download
- Transcript for Lexicon of Biochemical Reactions: Vitamin B6 / PLP Download
- Transcript for Ses 12: Respiration: ETOP Download
- Transcript for Session 16: Blood Sugar Fluctuations and Gluconeogenesis Download
- Transcript for Motivating Students to Study Metabolic Biochemistry with Oncology Applications Download
- Transcript for Session 4: Problem Set 3, Question 2: Proteases: Mechanisms of Inhibition Download
- Transcript for Session 13: Respiration: Proton Pumps and ATP Synthesis Download
- Transcript for Session 1: Problem Set 1: Sizes and Equilibria Download
- Transcript for Session 16: When Your Breath Smells Like Nail Polish Remover Download
- Transcript for Session 19: Problem Set 10, Problem 3: Gluconeogenesis Download
- Transcript for Research Focus: Genetic Change Download
- Transcript for Ses 14: Lipid Catabolism: Fatty Acid Beta-Oxidation Download
- Transcript for Session 12: Respiration: ETOP Download
- Transcript for ses20: Carbohydrate Biosynthesis III: Pentose Phosphate Pathway Download
- Transcript for Problem Set 7, Problem 1: Tracing Labels through Pathways Download
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Course outline
Instructor Insights · Videos
Research Focus: Ribonucleotide Reductases (RNRs)
Instructor Insights · Videos
Becoming a Toxicologist
Instructor Insights · Videos
Research Focus: Genetic Change
Instructor Insights · Videos
Focusing on the Morphological Unit of Life
Instructor Insights · Videos
Using a Vitamin Bottle as a Teaching Tool
Instructor Insights · Videos
Teaching Central Pathways to Help Students Understand Metabolism
Instructor Insights · Videos
Why Students Should Memorize Amino Acid Side Chains
Instructor Insights · Videos
Motivating Students to Study Metabolic Biochemistry with Oncology Applications
Instructor Insights · Videos
Advice for Next Teaching Generation: Focus Curricula on the Microbial World
Session 1 · Problem-solving Videos
Session 1: Problem Set 1: Sizes and Equilibria
Session 4 · Problem-solving Videos
Session 4: Problem Set 3, Question 2: Proteases: Mechanisms of Inhibition
Session 7 · Problem-solving Videos
Session 7: Problem Set 5, Problem 5: How Mannose, an Isomer of Glucose, Enters Glycolysis
Session 9 · Lecture Videos
Session 9: Glycolysis and Early Stages of Respiration
Session 11 · Lecture Videos
Session 11: Maintenance of Redox Neutrality
Session 13 · Lecture Videos
Session 13: Respiration: Proton Pumps and ATP Synthesis
Session 14 · Lecture Videos
Session 14: Lipid Catabolism: Fatty Acid Beta-Oxidation
Session 17 · Lecture Videos
Session 17: Fatty Acid and Lipid Biosynthesis
Session 18 · Lecture Videos
Session 18: Carbohydrate Biosynthesis I: Glycogen Synthesis
Session 20 · Lecture Videos
Session 20: Carbohydrate Biosynthesis III: Pentose Phosphate Pathway
Session 21 · Lecture Videos
Session 21: Regulation of Metabolism
Resource Index · Video
Lexicon of Biochemical Reactions: Introduction
Resource Index · Video
Lexicon of Biochemical Reactions: Cofactors Formed from Vitamin B12
Resource Index · Video
Lexicon of Biochemical Reactions: Vitamin B6 / PLP
Resource Index · Video
Lexicon of Biochemical Reactions: Redox Cofactors
Resource Index · Video
Problem Set 1, Problem 1: Sizes and Equilibria
Resource Index · Video
Lecture 5: Enzymes and Catalysis
Resource Index · Video
Problem Set 3, Question 2: Proteases: Mechanisms of Inhibition
Resource Index · Lecture Videos
Session 5: Carbonyl Chemistry
Resource Index · Video
Problem Set 5, Problem 5: How Mannose, an Isomer of Glucose, Enters Glycolysis
Resource Index · Video
ses 8: Intro to Sugar Chemistry and Carbohydrate Catabolism
Resource Index · Video
ses 9: Glycolysis and Early Stages of Respiration
Resource Index · Video
ses 10: Respiration: TCA Cycle
Resource Index · Video
Ses 11: Maintenance of Redox Neutrality
Resource Index · Video
PLP (Pyridoxal Phosphate) Chemistry
Resource Index · Video
Ses 13: Respiration: Proton Pumps and ATP Synthesis
Resource Index · Video
Ses 14: Lipid Catabolism: Fatty Acid Beta-Oxidation
Resource Index · Video
Ses 15: Special Cases in Fatty Acid Metabolism
Resource Index · Video
Session 16: Ketogenesis, Diabetes and Starvation
Resource Index · Video
Ses 17: Fatty Acid and Lipid Biosynthesis
Resource Index · Video
ses19: Carbohydrate Biosynthesis II: Gluconeogenesis
Resource Index · Video
ses20: Carbohydrate Biosynthesis III: Pentose Phosphate Pathway
Resource Index · Video
ses21: Regulation of Metabolism
MIT OpenCourseWare, Prof. John Essigmann, Prof. Joanne Stubbe, Dr. Bogdan Fedeles, 5.07SC Biological Chemistry I, Fall 2013.
License: CC BY-NC-SA 4.0 · Edition: Fall 2013 · Open the original course on OCW ↗
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