MIT OpenCourseWare

Browse materialsMIT 5.12 · Spring 2005

Organic Chemistry I

Subjects: Chemistry · Organic Chemistry

Art: Lascelles, Henry; Paas, John, 1790-1832, Plate II: The Modern Chemical Apparatus. No.2, 1800 · Public domain

Instructors: Dr. Kimberly Berkowski, Prof. Sarah O’Connor
Term: Spring 2005
Level: Undergraduate
What's inside: 8 problem sets · 1 reading · 1 handout · 46 other files · 4 web pages
Materials open: MIT OCW

Other versions of this course

5.12 · Spring 2005 · Study here (this version)
5.12 · Spring 2003 · Study here

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Start course: Lecture 1: Introduction to Organic Chemistry, Review, Molecular…Find a topic

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About this course

Source: MIT OpenCourseWare 5.12 Organic Chemistry I, Spring 2005, Dr. Kimberly Berkowski, Prof. Sarah O’Connor — original course page on ocw.mit.edu ↗. License: CC BY-NC-SA 4.0. Study order: MIT's own listing order, section by section. Taken from MIT's published course files, downloaded from ocw.mit.edu on September 23, 2026. How RedLectern is built.

Materials are grouped the way MIT organized them. A verified, course-wide order has not been established here.

Before you start

Prerequisites are not listed here. Check MIT's own syllabus for this course.

How this course was organized

What's here, and what isn't

A lecture sequence of 35 items is confirmed. Assignment and exam materials exist too, but MIT's own order for them could not be verified, so they're shown as materials below rather than a sequence.

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2 items from the source could not be safely included:

Referenced in a table, but without MIT's own verified order, so it isn't used to claim a sequence. (2 items)

Materials by section

Grouped by section, as MIT organized them. Not sequenced or ordered.

Assignments

16 problem sets

Exams

10 files

Lecture Handouts

25 files

Other materials from this course

MIT OpenCourseWare, Dr. Kimberly Berkowski, Prof. Sarah O’Connor, 5.12 Organic Chemistry I, Spring 2005.

License: CC BY-NC-SA 4.0 · Edition: Spring 2005 · Open the original course on OCW ↗

Organized by RedLectern, independent of MIT and not endorsed by MIT.

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Organic Chemistry I

Before you start

What's here, and what isn't

Not included here

Materials by section

Assignments

Exams

Lecture Handouts

Other materials from this course

Lecture 1: Introduction to Organic Chemistry, Review, Molecular Structure

Lecture 2: Resonance, Acidity and Basicity

Lecture 3: Alkanes and Isomerism

Lecture 4: Conformational Analysis of Alkanes

Lecture 5: Conformational Analysis of Cycloalkanes

Lecture 6: Stereochemistry I

Lecture 7: Stereochemistry II, Overview of Chemical Reactions I

Lecture 8: Overview of Chemical Reactions II

Lecture 9: Thermodynamics, Kinetics, Reaction Coordinate Diagrams

Lecture 10: Alkenes

Lecture 11: Electrophilic Addition to Alkenes (EAA): Carbocation Intermediate (Mechanism, Regiospecificity, Carbocation Stability, Hammond Postulate)

Lecture 12: EAA: Stereochemistry, Rearrangements

Lecture 13: EAA: 3-Membered Ring Intermediate

Lecture 14: EAA: Concerted Mechanism

Lecture 15: Alkene Cleavage, Addition of HBr (radical)

Lecture 16: Alkynes

Lecture 17: Reactions of Alkynes

Lecture 18: Alkyl Halides

Lecture 19: Alkyl Halides, Nucleophilic Substitution Reactions

Lecture 20: Alkyl Halides, Nucleophilic Substitution Reactions (cont.)

Lecture 21: Alkyl Halides, Nucleophilic Substitution Reactions (cont.)

Lecture 22: Alkyl Halides: Elimination Reactions, Aromaticity

Lecture 23: Alkyl Halides: Elimination Reactions, Aromaticity (cont.)

Lecture 24: Alkyl Halides: Elimination Reactions, Aromaticity (cont.)

Lecture 25: Aromaticity

Lecture 26: Electrophilic Aromatic Substitution

Lecture 27: Electrophilic and Nucleophilic Aromatic Substitution

Lecture 28: Electrophilic and Nucleophilic Aromatic Substitution (cont.)

Lecture 29: Alcohols and Phenols, Introduction to Catalysis

Lecture 30: Alcohols and Phenols, Introduction to Catalysis (cont.)

Lecture 31: Alcohols and Phenols, Introduction to Catalysis (cont.)

Lecture 32: Carbonyl Chemistry

Lecture 33: Carbonyl Chemistry (cont.)

Lecture 34: Multistep Synthesis

Lecture 35: Multistep Synthesis (cont.)