MIT OpenCourseWare

Browse materialsMIT 8.591J · Fall 2014

Systems Biology

Subjects: Biology · Physics

Art: Reinier Vinkeles / Pieter Pietersz Barbiers II, De zaal der physica van Felix Meritis, 1794 · Public domain

Instructor: Prof. Jeff Gore
Term: Fall 2014
Level: Undergraduate, Graduate
What's inside: 24 videos · 10 problem sets · 6 exams · 2 readings · 24 other files · 7 web pages
Materials open: Videos here · files on MIT OCW

Other versions of this course

8.591J · Fall 2014 · Study here (this version)
8.591J · Fall 2004 · Study here

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About this course

Source: MIT OpenCourseWare 8.591J Systems Biology, Fall 2014, Prof. Jeff Gore — original course page on ocw.mit.edu ↗. License: CC BY-NC-SA 4.0. Study order: MIT's own listing order, section by section. Taken from MIT's published course files, downloaded from ocw.mit.edu on September 23, 2026. How RedLectern is built.

Materials are grouped the way MIT organized them. A verified, course-wide order has not been established here.

Before you start

Prerequisites are not listed here. Check MIT's own syllabus for this course.

This course’s cited books, in our reading lists: Nonlinear Dynamics and Chaos: With Applications to Physics, Biology, Chemistry, and Engineering

How this course was organized

What's here, and what isn't

MIT's own materials here did not support a verified, course-wide order, so they are grouped by section instead.

Not included here

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MIT's page format for this item wasn't recognized clearly enough to place it safely. (53 items)
Referenced in a table, but without MIT's own verified order, so it isn't used to claim a sequence.

Materials by section

Grouped by section, as MIT organized them. Not sequenced or ordered.

Assignments

10 problem sets

Exams

Other materials from this course

24 video transcripts

3 images

MIT OpenCourseWare, Prof. Jeff Gore, 8.591J Systems Biology, Fall 2014.

License: CC BY-NC-SA 4.0 · Edition: Fall 2014 · Open the original course on OCW ↗

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Systems Biology

Before you start

What's here, and what isn't

Not included here

Materials by section

Assignments

Exams

Other materials from this course

Introduction to the Class and Overview of Topics

Input Function, Michaelis-Menten kinetics, and Cooperativity

Autoregulation, Feedback and Bistability

Synthetic Biology and Stability Analysis in the Toggle Switch

Oscillatory Genetic Networks

Graph Properties of Transcription Networks

Feed-forward Loop Network Motif

Introduction to Stochastic Gene Expression

Causes and Consequences of Stochastic Gene Expression

Stochastic Modeling

Life at Low Reynolds Number

Robustness and Bacterial Chemotaxis

Robustness in Development and Pattern Formation

Microbial Evolution Experiments and Optimal Gene Circuit Design

Evolution in Finite Populations

Clonal Interference and the Distribution of Beneficial Mutations

Fitness Landscapes and Sequence Spaces

Evolutionary Games

Survival in Fluctuating Environments

Parasites, the Evolution of Virulence and Sex

Interspecies Interactions

Ecosystem Stability, Critical Transitions, and Biodiversity

Dynamics of Populations in Space

The Neutral Theory of Ecology