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Browse materialsMIT 3.051J · Spring 2006

Materials for Biomedical Applications

Subjects: Engineering · Science

Art: Georg Agricola, De re metallica - gold panning (125711726), 1556 · Public domain

Instructor: Prof. Anne Mayes
Term: Spring 2006
Level: Undergraduate
What's inside: 1 lecture note · 1 reading · 42 other files · 3 web pages
Materials open: MIT OCW

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Start course: Lecture 1: Course Introduction ( PDF ) Biomaterials Defined…Find a topic

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About this course

Source: MIT OpenCourseWare 3.051J Materials for Biomedical Applications, Spring 2006, Prof. Anne Mayes — original course page on ocw.mit.edu ↗. License: CC BY-NC-SA 4.0. Study order: MIT's own listing order, section by section. Taken from MIT's published course files, downloaded from ocw.mit.edu on September 23, 2026. How RedLectern is built.

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Prerequisites are not listed here. Check MIT's own syllabus for this course.

How this course was organized

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Grouped by section, as MIT organized them. Not sequenced or ordered.

Lecture Notes

26 files

Assignments

14 problem sets

Exams

MIT OpenCourseWare, Prof. Anne Mayes, 3.051J Materials for Biomedical Applications, Spring 2006.

License: CC BY-NC-SA 4.0 · Edition: Spring 2006 · Open the original course on OCW ↗

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Materials for Biomedical Applications

Before you start

What's here, and what isn't

Not included here

Materials by section

Lecture Notes

Assignments

Exams

Lecture 1: Course Introduction ( PDF ) Biomaterials Defined Structural Hierarchy in Materials and Biology

Lecture 2: Biomaterials Surfaces: Physics ( PDF ) Surface (vs. Bulk) Structure and Properties Surface Energy Adsorption, Segregation, and Reconstruction at Surfaces

Lecture 3: Biomaterials Surfaces: Chemistry ( PDF ) Reactions at Surfaces: Chemisorption, Corrosion

Lecture 4: Biomaterials Surfaces: Chemistry (cont.) ( PDF ) Hydrolysis (Dr. Taniguchi) ( PDF - 1.3 MB )

Lecture 5: Protein-Surface Interactions ( PDF ) Proteins: Structure, Properties, Functions Protein Adsorption: Langmuir Model

Lecture 6: Protein-Surface Interactions (cont.) ( PDF ) Protein Adbsorption: Complex Phenomena, Measurement

Lecture 7: Cell-Surface Interactions: Host Response to Biomaterials ( PDF - 1.3 MB ) Cell Adhesion Mechanisms Coagulation Cascade

Lecture 8: Cell-Surface Interactions: Host Response to Biomaterials (cont.) ( PDF ) Immune Response: Alternative Complement Activation

Lecture 9: Surface Modification Methods ( PDF ) Purposes Plasma Treatments Organic Coatings (Dr. Taniguchi) ( PDF )

Lecture 10: Surface Modification Methods (cont.) ( PDF ) Polymer Coatings Patterned Surfaces

Lecture 11: Surface Characterization ( PDF ) In Vacuum: XPS/ESCA, AES, SIMS

Lecture 12: Surface Characterization In situ ( PDF ) Contact Angle, AFM

Lecture 13: Quantifying Cell Behavior ( PDF ) Cell Cultures Cellular Assays: Adhesion, Migration, Proliferation

Lecture 14: Quantifying Cell Behavior (cont.) ( PDF ) Cellular Assays: Differentiation, Function

Lecture 15: Statistical Analysis ( PDF ) Error Sources, Distribution Functions, t- test

Lecture 16: Statistical Analysis (cont.) ( PDF ) Fisher Test, Regression Methods

Lecture 17: Biosensors and Diagnostic Devices ( PDF ) Biological Elements Transduction Mechanisms Properties Examples: Fiber Optic Biosensors, Nanobarcodes

Lecture 18: Drug Delivery: Controlled Release (Dr. Taniguchi) ( PDF ) Chemically-controlled Devices

Lecture 19: Drug Delivery: Controlled Release (cont.) ( PDF ) Diffusion-controlled, Membrane-based and Osmotic Devices

Lecture 20: Drug Delivery: Controlled Release (cont.) ( PDF ) Methods: Transdermal, Colloidal Vehicles Mechanical Pumps

Lecture 21: Biomaterials for Organ Replacement ( PDF ) Organ Replacement Therapies Mechanical Properties Bone Substitutes

Lecture 22: Tissue Engineering ( PDF ) Cell Types Approaches: In vitro, In vivo, Ex vivo/Cell Encapsulation Scaffolds: Design and Fabrication

Lecture 23: Tissue Engineering (cont.) ( PDF ) Case Examples: Artificial Pancreas, Cartilage, Nerve Regeneration

Lecture 24: FDA Regulatory Issues and Course Evaluations ( PDF )