The opening of I. ON THE PHYSIOLOGICAL ACTION OF POISONS
I shall discuss this subject by considering first the mode in which poisons act, and secondly, the causes by which their action is liable to be modified.
SECTION I.—On the Mode of Action of Poisons.
On attending to the effects which follow the application of a poison to the body, we perceive that they are sometimes confined to the part where it is applied, and at other times extend to distant organs. Hence the action of poisons may be naturally considered as local and remote.
The local effects of poisons are of three kinds. Some decompose chemically or corrode the part to which they are applied. Others, without immediately injuring its organization, inflame or irritate it. Others neither corrode nor irritate, but make a peculiar impression on the sentient extremities of the nerves, unaccompanied by any visible change of structure.