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A laboratory guide in pharmacology

Torald Hermann Sollmann · 1917 · Scanned text · Free in the US

156,654 words · about 10 h 58 min to read

Period artwork: Interior of the Bodleian Library, 1845
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Free in the US: this text is in the public domain in the United States; it may still be in copyright elsewhere.

Licence: PD · Library of Congress states the book is in the public domain and free to use and reuse (https://data.labs.loc.gov/digitized-books/README.html); published 1917, public domain asserted for the US only · Library of Congress, Selected Digitized Books (https://www.loc.gov/item/17005565); text via the Common Pile (CC BY 4.0 compilation, per-document rights preserved)

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About this book

Author
Torald Hermann Sollmann
Language
English
Published
1917
Length
156,654 words · about 10 h 58 min
Sections
87 reader sections
Text
Scanned text, read from page scans by OCR; may contain errors
Rights
Public domain in the United States

 

Contents (87)
  1. Preface about 1 min
  2. II under 1 min
  3. Chapter XXXVII under 1 min
  4. CHAPTER XLVI Intestinal Osmosis — Diuresis — Treatment of Acute Cardiac Lesions 289 about 20 min
  5. Chapter I General Reactions Of Plant Constituents about 3 min
  6. Chap. I General Reactions Of Plant Constituents 37 Exercise Ii.— Glucosids about 7 min
  7. Chapter II Pharmaceutic Preparations And Dispensing about 9 min
  8. Chapter III Incompatibility about 5 min
  9. Chapter IV Isolation Of Poisons about 2 min
  10. Chap. IV about 6 min
  11. Chapter V Special Tests Of Important Alkaloids about 1 min
  12. Chap. V Special Tests Of Important Alkaloids 55 about 13 min
  13. Chapter VI Special Tests For Important Glucosids And Neutral about 3 min
  14. Chapter VII Special Tests Of Important Aromatic Derivatives about 2 min
  15. Chap. VII Important Aromatic Derivatives 63 about 7 min
  16. Chapter VIII Special Tests Of Important Aliphatic Derivatives about 7 min
  17. Chap. VIII Important Aliphatic Derivatives 69 about 10 min
  18. Chapter IX Specific Tests Of Important Heavy Metals about 10 min
  19. Chap. X Special Reactions Of Earthy And Alkali Metals 77 about 1 min
  20. Chapter X Special Reactions Of Earthy And Alkali Metals about 2 min
  21. CHAPTER XI CAUSTIC MINERAL ACIDS AND ALKALIES; PEROXIDS All the exercises are optional about 1 min
  22. Chapter XII Special Reactions Of Inorganic Acid Radicals about 3 min
  23. Chap. XII Special Reactions Of Inorganic Acid Radicals 8 1 about 7 min
  24. Chapter XIII Flavors about 1 min
  25. Chap. XIII Flavors 8$ Exercise Iii.— Comparison Of Water And Milk about 3 min
  26. Chapter XIV (demonstration) Colors; (optional) Detection Of Colors In Foods, Etc about 5 min
  27. Chapter XV Chemic Study Of The Excretion Of Drugs In Man about 2 min
  28. Chap. XV Chemic Study Of The Excretion Op Drugs In Man 9 1 about 8 min
  29. Chap. XVI Chemic Antidotes 95 Exercise Xvi.— Form Of Administration Of Insoluble Esters about 1 min
  30. Chapter XVI Chemic Antidotes about 2 min
  31. Chap. XVII Adsorption By Colloids 97 under 1 min
  32. Chapter XVII Adsorption By Colloids about 2 min
  33. Chapter XVIII (demonstration) Selective Solvents under 1 min
  34. Chap. XVIII Selective Solvents 99 Exercise I.— Distribution Coefficient about 3 min
  35. CHAP. XIX OSMOSIS AND DIFFUSION lOI CHAPTER, XIX about 9 min
  36. CHAP. XX DETERMINATION OF MOLECULAR CONCENTRATION IO5 (e) What causes the water to rise in the osmometer or egg? about 1 min
  37. Chapter XX (optional) Determination Of Molecular Concentration about 5 min
  38. Chapter XXI Aggregation Of Colloids about 2 min
  39. CHAP. XXII HEMOLYSIS, CRENATION, AND AGGLUTINATION lOQ EXERCISE III.— (OPTIONAL) ELECTROLYTES ON HEAT COAGULATION about 1 min
  40. Chapter XXII Hemolysis, Crenation, And Agglutination Of Red about 3 min
  41. CHAP. XXIII (optional) ANTIBODIES III about 2 min
  42. Chapter XXIII (optional) Antibodies about 3 min
  43. Chapter XXIV (optional) Effects Of Drugs On Hemoglobin about 5 min
  44. Chap. XXV Chemic Effects Of Corrosives And Irritants I15 about 1 min
  45. Chapter XXV Chemic Effects Of Corrosives And Irritants about 6 min
  46. Chapter XXVI Physiologic Effects Of Irritants about 4 min
  47. Chap. XXVIII Antiseptics 121 about 1 min
  48. Chapter XXVII (optional) Cathartics On Man about 1 min
  49. Chapter XXVIII Antiseptics about 3 min
  50. Chapter XXIX Effects Of Drugs On Ferments * about 1 min
  51. Chap. XXIX Effects Of Drugs On Ferments 12$ Exercise I.— Coagulation Of Milk about 4 min
  52. CHAP. XXX MONOCELLULAR ORGANISMS AND LEUKOCYTES 1 27 EXERCISE v.— DIGESTIVE AND SIMILAR FERMENTS about 2 min
  53. Chapter XXX Monocellular Organisms And Leukocytes about 3 min
  54. Chapter XXXI Anthelmintics And Insecticides about 5 min
  55. Chapter XXXII Localization Of Actions; Stimulants And Depressants about 1 min
  56. Chap. XXXII about 37 min
  57. Chapter XXXIII Muscular Contraction: Skeletal Muscle, Cilia about 1 min
  58. Chap. XXXIII Muscular Contraction: Skeletal Muscle, Cilia about 19 min
  59. Chap. XXXIV Smooth Muscle: Intestine, Uterus, And Arteries 1 59 Exercise X.— (demonstration Or All Groups) Astringents about 1 min
  60. Chapter XXXIV Smooth Muscle: Intestine, Uterus, And Arteries about 16 min
  61. Chap. XXXV Reactions Of Blood-vessels 167 about 2 min
  62. Chapter XXXV Reactions Of Blood-vessels (perfusion Experiments about 29 min
  63. Chapter XXXVI Excised And Frog Hearts Introductory about 3 min
  64. Chap. XXXVI Excised And Erog Hearts 1 83 about 44 min
  65. Chapter XXXVII about 2 min
  66. Chap. XXXVII Autonomic Drugs 203 about 16 min
  67. Chap. Xxxviii Fate Of Drugs) Idiosyncrasy; Emetics 211 Exercise Xvi.— (optional) Experimental Pleurisy under 1 min
  68. Chapter Xxxviii about 22 min
  69. Chapter XXXIX about 24 min
  70. Chap. XL Convulsants And Treatment Of Poisoning 235 about 1 min
  71. Chapter XL Convulsants And Treatment Of Poisoning about 6 min
  72. CHAP. XLI RESPIRATION (aND BLOOD-PRESSURE) 239 EXERCISE IX.— (GROUP II, B) ARTIFICIAL RESPIRATION AND STRYCHNIN about 1 min
  73. Chapter XLI Respiration (and Blood-pressure) about 31 min
  74. Chapter XLII Administration Of Anesthetics On Circulation And about 2 min
  75. Chap. XLII about 14 min
  76. Chap. XLIII Vasomotor Drugs 265 about 1 min
  77. Chapter XLIII Vasomotor Drugs; Treatment Of Circulatory Collapse about 26 min
  78. Chap. XLIV Changes In Heart-rate, Etc about 1 min
  79. Chapter XLIV Changes In Heart-rate, Etc about 9 min
  80. Chapter XLV Myocardial Depressants And Tonics Exercise I.— (group I) Cardiac Depressants On Blood-pressure under 1 min
  81. CHAP. XLV MYOCARDIAL DEPRESSANTS AND TONICS 285 Apparatus. — Damped mercury manometer; oncometer; injection buret about 7 min
  82. Chapter XLVI Intestinal Osmosis-diuresis— Treatment Of Acute about 21 min
  83. CHAPTER I *Nicotin, i per cent 5 under 1 min
  84. CHAPTER II Cinnamon Oil, in drop bottles 5 under 1 min
  85. CHAPTER V **Strychnin Sulphate, i : 50,000 30 under 1 min
  86. CHAPTER VIII **Formaldehyd, i : 50,000 25 about 15 min
  87. IV XVI about 1 h 34 min

Continue:

Preface

The following exercises are designed to introduce the student personally to some of the more important facts of pharmacology. They have been selected so as to present little difficulty to one versed in ordinary chemic and physiologic technic, and require but little help on the part of the instructor.

The pharmaceutic and toxicologic exercises (Part I) are confined strictly to the bare essentials needed by students who intend to become general practitioners of medicine. Especial stress has been laid on the facts which have a direct practical bearing.

The experiments on animals (Part II) have been arranged in groups, to illustrate various types or phenomena, to bring out the similarities and differences of the response of organs to pharmacologic agents, rather than by individual drugs. This arrangement articulates better with the student's experience in physiology and pathology, on which pharmacology is largely founded. It is, therefore, more natural, as well as more interesting and inspiring. It has been the practice of the author to have this experimental course precede the didactic course. The latter, dealing with individual drugs, can then be based upon phenomena with which the student is already familiar.

The exercises are arranged for a course of thirty working periods of two to three hours. Additional experiments, for longer courses, demonstrations, etc., are introduced as optional. They can, of course, be indefinitely extended by the use of dose tables and of the "Technical Notes." These are intended primarily for the instructor and investigator, indicating the sources where more detailed information and different methods may be found.

II

THE USE IN THIS VOLUME OF CERTAIN PORTIONS OF THE TEXT OF THE UNITED STATES PHARMACOPOEIA IS BY VIRTUE OF PERMISSION RECEIVED FROM THE BOARD OF TRUSTEES OF THE UNITED STATES PHARMACOPOEIAL CONVENTION. THE SAID BOARD OF TRUSTEES IS NOT RESPONSIBLE FOR ANY INACCURACY OF QUOTATION NOR FOR ANY ERRORS IN THE STATEMENT OF QUANTITIES OR PERCENTAGE STRENGTHS.

Chapter XXXVII

Autonomic Drugs: (A) Pupils; (B) Glands; (C) Bronchioles; (D) Anaphylaxis:

(E) ExuDATPVE Inflammation 202

CHAPTER XXX\ III

Fate of Drugs; Idiosyncrasy; Emetics: (A) Absorption; (B) Excretion; (C) Distribution and Interaction of Drugs; (D) Idiosyncrasy; Atropin Thyroid Test; (E) Emetics; (F) Antemetics 211

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