Pharmacology, clinical and experimental; a groundwork of medical treatment, being a text-book for students and physicians

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CHAPTER II Pharmacology of the Central Nervous System (Gottlieb) 11

Excitants — Strychnine — General Discussion of Alkaloids — Convulsants — Cerebral Excitants — Delirifacients — Depressants — Morphine Group. Alcohol-chloroform Group: Alcohol — General Anaesthetics — Ether — Chloroform — Combined Anaesthesia — Nitrous Oxide — Ethyl Bromide. Hypnotics of Alcohol-chloroform Group : Insomnia — Chloral — Other Hypnotics.

Relationship between Constitution and Pharmacological Action: Theory of Narcosis (Meyer) — Other Central Depressants — Aconitine — Magnesium Salts — Bromides — Valerian.

CHAPTER III Pharmacology of the Sensory Nerve-endings (Gottlieb) 117

Stimulants — Local Anaesthesia — Cocaine — Substitutes for Cocaine.

CHAPTER IV Pharmacology of the Vegetative Nervous System (Gottlieb) 136

The Sympathetic Nervous System — Autonomic or Parasympathetic Nervous System — Common Reaction to Nicotine — Antagonistic Functions of the Two Systems — Epinephrin a "Sympathetic" Drug — Autonomic Drugs.

CHAPTER V Pharmacology of the Eye (Meyer) 144

Pharmacology of the Retina — Of the Iris and Ciliary Muscles — Central Mydriatics and Miotics — Peripheral Miotics — Physostigmine — Pilocarpine — Other Miotics — Peripheral Mydriatics — Atropine — Substitutes for Atropine — Cocaine — Epinephrin — Astringents and Corrosives — Abrin — Dionin and Peronin.

CHAPTER VI Pharmacology of the Digestion (Meyer) 162

Pharmacology of the Digestive Glands: Salivary Secretion — Reflex and Direct Excitation — Inhibition — Elimination by Saliva — Gastric Secretion — Stimulation and Inhibition — Pancreatic Secretion — Internal Secretion — The Secretion of the Bile; — Cholagogues — Elimination and Antisepsis — Other Liver Functions — The Secretion of the Intestinal Juice — Elimination — Absorption in the Alimentary Canal — In the Stomach — In the Intestine — Absorption of Salts.

Mechanics of Digestion: Deglutition — Movements of the Stomach — Emesis — Central Emetics — Apomorphine — Peripheral Emetics — Ipecac — Copper Sulphate — Zinc Sulphates — Tartar Emetic — Treatment of Vomiting — Normal Movements — Drugs Stimulating These — Inhibition of Gastric Movements — Atropine and Morphine.

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Movements of Intestines: Autonomic Drugs — Sympathetic Drugs — Atropine and Morphine.

Cathartics: Classification — Cathartics Interfering with Absorption — Sat lines — Calomel — Cathartics Acting on Small Intestine — Castor Oil — Croton Oil — Jalap, Scammony, Colocynth, Gamboge, Podophyllin — Cathartics Acting on Large Intestine — Senna, Cascara, Rhubarb, Aloes, Phenolphthalein, Sulphur — Carminatives.

Obstipants — Astringents — Tannin — Metallic Salts.

CHAPTER VII Pharmacology of the Reproductive Organs (Gottlieb) 218

Nervous and Chemical Correlation — Influence of Testicles and Ovaries — Erection — Yohimbin — Mammary Glands — Lactogogues — Elimination in Milk.

Pharmacology of Uterine Movements — Peripherally Acting Drugs — Oxytoxics, Central and Reflex — Ergot — Hydrastis — Epinephrin — Hypophysis Extracts.

CHAPTER VIII Pharmacology of the Circulation (Gottlieb) 231

Factors Controlling the Circulation — Methods of Investigation. Pharmacology of the Heart: Cardiac Functions — Actions on Centres of the Extracardial Nerves — Drugs Acting on Peripheral Vagus — Nicotine — Choline and Muscarine — Atropine — Physostigmine — Actions on Accelerator in Periphery — Cardiac Depressants — Cardiac Stimulants — Camphor — Ether — Alcohol — Epinephrin — Digitalis — Caffeine — Other Factors. Pharmacology of the Vessels: Central Vasoconstricting Drugs — Caffeine,' Camphor, etc. — Alcohol — Ether — Central Vasodilating Drugs — Amyl Nitrite — Peripheral Vasoconstricting Drugs — Epinephrin — Digitalis Bodies — Peripheral Vasodilating Drugs — Capillary Dilators — Yohimbin — Caffeine — Local Applications.

Pharmacology of the Circulation as a Whole: Theory of the Action of Digitalis — Practical Employment — Active Principles — Chemical Assay — Physiological Assay — Cumulation — Dosage — Preparations — Treatment of Cardiac and Vascular Depression — Treatment of Vasoconstriction.

CHAPTER IX Pharmacology of the Respiratory System (Meyer) 332

Actions of C0 2 and 2 — Direct or Central Stimulants — Respiratory Sedatives — Morphine — Expectorants — Treatment of Asthma.

CHAPTER X Pharmacology of the Renal Function (Meyer) 349

Physiology of Diuresis — Factors Controlling Diuresis — Hydraemia — Blood Flow through Kidney — Caffeine Group — Digitalis Group — Agents Acting on the Tubules — Urinary Antiseptics — Alkalies — Atophan.

CHAPTER XI Pharmacology of the Secretion of Sweat (Gottlieb) 369

Physiology — Diaphoretics, Central and Peripheral — Antisudorifics.

CHAPTER XII Pharmacology of the Metabolism (Meyer) 377

General Considerations — Increased Assimilation — Altered Metabolism —

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The Effects of Body Temperature and of Light and Radiant Energy — Water and Salts — Alkalies — Acids — Thyroid — Iodine — Quinine — Substances, Inhibiting Oxidation — Phosphorus — Arsenic — Antimony — Iron and Mercury — Lecithin — Certain Phases of Metabolism — Carbohydrate Metabolism — Purine Metabolism.

CHAPTER XIII Pharmacology of the Muscles (Meyer) 422

Physiology" "and Anatomy — Strychnine — Muscular Depressants — Stimulants — Caffeine — Alcohol — Alcohol as a Food — Testicular Extracts.

CHAPTER XIV Pharmacology of the Blood (Meyer) 435

Infusions — Iron — Manganese and Arsenic — High Altitudes — Agents Affecting the Leucocytes — Coagulation — Viscosity — Chemical Composition and Alkalinity — Toxicology of the Blood — CO and HCN — Haemolysis.

CHAPTER XV Pharmacology of Heat Regulation (Gottlieb) 453

Physiology — Fever — Action of Antipyretics in Fever — Cold Baths — Action of Antipyretics on Heat Production and Loss — Antipyrine Group — Quinine — Salicylates — Other Agents — Therapeutic Employment — Quinine — Antipyrine Group — Salicylic Acid Group.

CHAPTER XVI Pharmacology of Inflammation (Meyer) 481

Nature and Significance of Inflammation — Cutaneous Irritants — Excitants of Inflammation — Vascular Poisons — Caustics — Therapeutic Employment and Mode of Action — Counterirritants — Vesicants and Suppurants — Caustics or Escharotics — Inhibition of Inflammation — Analgesic Antiphlogistic Agents — Astringents — Lime Salts — Epinephrin — Quinine.

CHAPTER XVII Etiotropic Pharmacological Agents (Gottlieb) 497

General Antiseptics and Disinfection — Anthelmintics — Specific Disinfectants — Creosote in Tuberculosis — Quinine in Malaria — Salicylic Acid in Rheumatism — Arsenical Compounds in Protozoal Diseases — Mercury in Syphilis — Antitoxins — Vaccination against Rabies — Tuberculin — Serum Therapy — Toxins — Antitoxins — Ehrlich's Side-chain Theory — Antitoxic Sera — Tetanus — Diphtheria — Bacteriolysins — Agglutinins and Cytotoxins.