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A manual of clinical diagnosis by means of microscopic and chemical methods, for students, hospital physicians, and practitioners

Charles E. Simon · 1907 · Scanned text · Free in the US

283,524 words · about 19 h 51 min to read

Period artwork: Interior of the Bodleian Library, 1845
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Licence: PD · Library of Congress states the book is in the public domain and free to use and reuse (https://data.labs.loc.gov/digitized-books/README.html); published 1907, public domain asserted for the US only · Library of Congress, Selected Digitized Books (https://www.loc.gov/item/07023959); text via the Common Pile (CC BY 4.0 compilation, per-document rights preserved)

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About this book

Author
Charles E. Simon
Language
English
Published
1907
Length
283,524 words · about 19 h 51 min
Sections
15 reader sections
Text
Scanned text, read from page scans by OCR; may contain errors
Rights
Public domain in the United States

 

Contents (15)

Continue:

Front matter

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Chapter I. The Blood

PAGE

General considerations 17 color 17

odor 18 determination according to Hammerschlag 18

determination according to Schmaltz and Peiper 19

indirect estimation of the hemoglobin 19

reaction . 20

estimation of the alkalinity according to Lowy 21

estimation of the alkalinity according to Engel 21

estimation of the alkalinity according to Dare 22

Chemical examination of the blood 25

general chemistry of the blood 25

coagulation of the blood 27

blood pigments . 29

hemoglobin and oxyhemoglobin 29

hemoglobinemia 33

carbon monoxide hemoglobin 34

nitric oxide hemoglobin 35

hydrogen sulphide hemoglobin 35

carbon dioxide hemoglobin 35

hematin 35

hemin 36

methemoglobin 37

hematoidin 38

hematoporphyrin 38

the proteids of the blood 39

the carbohydrates 40

sugar . 40

estimation of the sugar in the blood 41

Williamson's diabetic blood test . . 42

glycogen 42

cellulose 42

urea 42

uremia . 43

ammonia 43

uric acid and xanthin bases 43

fat and fatty acids 45 biliary constituents 49 cholin 50 the red corpuscles 51

variations in the size of the red corpuscles 51

variations in the form of the red corpuscles ....... 52 viii CONTENTS

Microscopic examination of the blood — Continued. page

variations in the color of the red corpuscles and color index . . 53

variations in the number of the red corpuscles 54

behavior toward aniline dyes (polychromatophilia) .... 60

granular degeneration ' 61

Cabot's ring bodies 64

Ehrlich's hemoglobinemic Innenkorper 65

nucleated red corpuscles 65

normoblasts 65

megaloblasts 67

the leukocytes 69

general differentiation of the various forms of leukocytes ... 69 differentiation of the leukocytes according to their behavior toward

aniline dyes . 70

the small mononuclear leukocytes 70

the large mononuclear leukocytes 73

the polynuclear neutrophilic leukocytes 74

the polynuclear eosinophilic leukocytes . 77

the mast-cells 78

the myelocytes 80

Tiirck's irritation forms (phlogocytes) 82

iodophilia 83

leukocytosis 84

polynuclear neutrophilic hyperleukocytosis 85

polynuclear neutrophilic hypoleukocytosis ....... 97

neutrophilic karyomorphism 101

polynuclear eosinophilic hyperleukocytosis 102

polynuclear eosinophilic hypoleukocytosis 108

lymphocytosis 109

lymphopenia 112

variations in number of the large mononuclear leukocytes . . . 112

variations in number of the mast-cells 113

myelocytosis 114

the plaques 118

the dust particles of Muller 120

General technique 120

slides and cover-glasses 120

the blood mount ........ 121

fixation 123

The aniline dyes and principles of staining . . . . 125

Methods of staining 129

the eosinate of methylene blue . . . . .129

Ehrlich's triacid stain 130

the Romanowsky methods . . ... . . . 132

method of Hastings 132

method of Leishman 134

method of Wright 135

method of Giemsa 136

method of Goldhorn 137

Demonstration of iodophilia 137 method of Simon ' 137

enumeration of the leukocytes 138

enumeration of the red cells .140

differential leukocyte counting .143

enumeration of the plaques 144

The hematokrit 144

volume index 147

Dare's hemoglobinometer . 148

FleischPs hemoglobinometer . 150

Gowers' hemoglobinometer (Sahli's modification) . . . . . . 152

Talquist's method 152

CONTENTS ix

TAGE

Estimation of blood iron 153

Kryoscopic examination of the blood 154

Osmotic resistance of the red cells 157 typhoid fever 159

agglutination test 160

paratyphoid fever 165

pneumonia 166

pyogenic bacteriemia 168

go nococcus septicemia 171

anthrax ... 172

acute miliary tuberculosis 173

glanders 174

Malta fever 174

bubonic plague . 175

malaria 177

trypanosomiasis 187

relapsing fever 189

typhus fever 190

Kala-azar . 190

syphilis 191

spotted fever . . 191

filariasis . f . . 191

distomiasis (bilharziasis) 195

anguilluliasis 196

Chapter II. The Secretions Of The Mouth

Saliva 198 chemistry of the saliva 198

microscopic examination of the saliva 199

pathological alterations 201

Special diseases of the mouth 202

tuberculosis of the mouth 202

actinomycosis 202

catarrhal stomatitis 202

ulcerative stomatitis 202

gonorrheal stomatitis 202

thrush 202

Tartar 203

Coating of the tongue 203 pharvngomvcosis leptothrica . 203

tonsillitis 204

Vincent's angina 204

diphtheria 205

scarlatina 208

glandular fever 208

Chapter III. The Gastric Juice And The Gastric Contents

The secretion of gastric juice 209

Test meals 210

the test breakfast of Ewald and Boas 210 x CONTENTS

Tests meals — Continued. page

the test breakfast of Boas 210

the test dinner of Riegel 210

the double test meal of Salzer 210

The stomach tube . ' 211

contra-indications to the use of the tube . 211

introduction of the tube 211

General characteristics of the gastric juice 213 the acidity of the gastric juice 214

determination of the acidity of the gastric juice 215

the amount of free hydrochloric acid 217

euchlorhydria 218

hypochlorhydria 218

anachlorhydria 218

hyperchlorhydria 218

test for free acids 219

test for free hydrochloric acid . . 219

the dimethyl-amino-azo-benzol test 219

the phloroglucin-vanillin test 220

the resorcin test 221

the tropeolin test " 221

the combined hydrochloric acid 222

quantitative estimation of the hydrochloric acid ....... 222

Topfer's method . ". ", 222

deficit of hydrochloric acid 223

Sahli's method 223

Martius and Liittke's method 224

Leo's method . 226

the ferments of the gastric juice and their zymogens 227

pepsin and pepsinogen 227

tests for pepsin and pepsinogen . . . . . . . . . 229 chymosin and chymosinogen 230

tests for chymosin and chymosinogen 231 analysis of the products of albuminous digestion . . . . . . 232

tests for the products of carbohydrate digestion . 233 mode of formation and clinical significance 233

tests for lactic acid 235

Kelling's test 235

Uffelmann's test . . . • 235

Strauss' test 236

Vournaso's test 236

Boas' test 237

quantitative estimation of lactic acid according to Boas' method 230

the fatty acids 240

mode of formation and clinical significance 241

tests for butyric acid 241

tests for acetic acid 242

quantitative estimation of the fatty acids 242

gases 244 vomited material 244

food material 246

mucus 246

gastrosuccorrhea mucosa 246

saliva 246

bile 246

pancreatic juice 247

blood 247

CONTENTS xi

Chemical examination of the gastric juice — Continued. page

test of Miiller and Weber 247

Donogany's method . . . . . 247

pus 248

stercoraceous material 248

parasites 249

odor . 249

Microscopic examination of the gastric contents 249

the Boas-Oppler bacillus 250

sarcinae 250

protozoa 251

shreds of mucous membrane 251

tumor particles 252

Examination of the motor power of the stomach 252

Leube's method 252

the salol test of Ewald and Sievers 253

Examination of the resorptive power of the stomach 253

Indirect examination of the gastric juice . . 254

Gimzburg's method 254

Chapter IV. The Feces

number of stools 256 consistence and form 257 color 258

aloin test 260

guajac test 261

macroscopic constituents 261

alimentary detritus 261

mucous cylinders 262

concretions 263

foreign bodies 265

microscopic constituents 265

constituents derived from food 266

morphological elements derived from the alimentary canal . . 270 blood corpuscles 271

crystals '271

mucus 273

Bacillus dvsenterise 276

Bacillus typhi 278

Bacillus acidophilus 280

Bacillus vulgaris 281

Bacillus pyocyaneus 282

Bacillus coli communis 282

Bacillus lactis aerogenes 283

Bacillus cholerse 283

Bacillus tuberculosis 285

Animal parasitology 286

protozoa 286

Entamoeba dvsenterise 286

Entamoeba coli 289

Paramceba hominis - 289

Cercomonas hominis 290

Trichomonas intestinalis 291

Megastoma entericum 292 xii CONTENTS

Animal parasitology — Continued. page

Balantidium coli 293

vermes 295

Taenia saginata 295

Taenia solium - 296

Taenia nana . . . . 297

Taenia diminuta 299

Taenia cucumerina 299

Taenia Africana 299

Taenia Madagascariensis 299

Bothriocephalic latus . . 300

Krabbea grandis 302

Distoma hepaticum " 302

Distoma lanceolatum . 302

Distoma Buskii 304

Distoma sibiricum 304

Distoma spatulatum 304

Distoma conjunctum 304

Distoma heterophyes 304

Amphistomum hominis 304

Ascaris lumbricoides 305

Ascaris mystax 307

Ascaris maritima 307

Oxyuris vermicularis 307

Uncinaria duodenalis ' . 307

Trichocephalus hominis 311

Trichina spiralis 311

Strongyloides intestinalis 312

Chemistry of the feces 316

reaction . . 316

chemical composition 317

phenol, indol, skatol 318

fatty acids 319 biliary acids . 320

pigments 320

purin bodies 322

mucin 322

albumin 323

albumoses 323

carbohydrates 323

ptomains 323

Meconium 323

Chapter V. The Nasal Secretion

Physiology and pathology of the nasal secretion 325

Chapter VI. The Sputum

General technique 326

General characteristics of the sputa 327 consistence 327

color 328

odor 328 configuration of sputa 329

CONTENTS

Xlll

PAGE

Macroscopic constituents of sputum 330

cheesy particles 330

elastic tissue 330

fibrinous casts 330

Curschmann's spirals : 332

echinococcus membranes 333

concretions . 333

foreign bodies 333 red blood corpuscles 335

epithelial cells 336

elastic tissue 337

Entamoeba dysenterise 339

Trichomonades . 339

Cercomonades 339

Taenia echinococcus 339

Distoma pulmonale 343

Distoma hematobium 343

vegetable parasites . 344

the tubercle bacillus 344

methods of staining 345

Weigert-Ehrlich's method 346

Ziehl-Neelsen's method 346

cultivation of tubercle bacillus 347

the Diplococcus pneumoniae 348

the bacillus of influenza . 349

the bacillus of whooping-cough . . . . . . . . 350

the smegma bacillus 351

the typhoid bacillus . . . 351

the plague bacillus : 351

Micrococcus catarrhalis 351

Micrococcus tetragenus 351

staphylococci and streptococci 351

streptothrices . . 351

actinomycosis 351

blastomycetes 353

moulds 353

Oidium albicans . 354

Sarcina pulmonalis 354

crystals '354

Charcot-Leyden crystals 354

hematoidin 356 fatty acid crystals 356

leucin and tyrosin 357

calcium oxalate 357

triple phosphates 357

the pneumoconioses 357

anthracosis 357

siderosis 358

chalicosis . 358

stycosis 358

Chemistry of the sputum 358

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