MIT OpenCourseWare
Fundamentals of Biology
- Instructors
- Prof. Eric Lander, Prof. Robert Weinberg, Prof. Tyler Jacks, Prof. Hazel Sive, Prof. Graham Walker, Prof. Sallie Chisholm, Dr. Michelle Mischke
- Term
- Fall 2011
- Level
- Undergraduate
- What's inside
- 86 videos · 4 exams · 138 other files · 29 web pages
- Materials open
- Videos here · files on MIT OCW
About this course
Source: MIT OpenCourseWare 7.01SC Fundamentals of Biology, Fall 2011, Prof. Eric Lander, Prof. Robert Weinberg, Prof. Tyler Jacks, Prof. Hazel Sive, Prof. Graham Walker, Prof. Sallie Chisholm, Dr. Michelle Mischke — original course page on ocw.mit.edu ↗. License: CC BY-NC-SA 4.0. Study order: MIT's own units, each a lecture sequence in MIT's listing order; no single course-wide order across units is claimed. Taken from MIT's published course files, downloaded from ocw.mit.edu on September 23, 2026. The “How to start this course” route below is taken from MIT's own pages for this course, as fetched on September 25, 2026. How RedLectern is built.
Study route
How to start this course
Words in quotation marks are MIT’s own, from its pages for this course, linked under each part. The headings, labels and links are RedLectern’s.
Before you start
- “There are no formal prerequisites for this course. At MIT, it is usually taken during the freshman (first) year.”
MIT's own preparation:
What you'll learn
- “Identify the general structure and function of carbohydrates, phospholipds, proteins, enzymes and nucleic acids.”
- “Outline the general processes used by the cell to generate cellular energy from sugar and to generate the energy and reducing agent needed for the Calvin cycle.”
- “Describe how DNA was shown to be the genetic material and how DNA is copied.”
- “Describe the structure and regulation of genes, and the structure and synthesis of proteins.”
- “Understand the inheritance of two or more traits based upon Mendelian genetics. Apply this knowledge to drawing and decoding human pedigrees.”
- “Understand the general tools and reagents used in recombinant DNA technologies.”
Time
- “MIT expects its students to spend about 150 hours on this course.”
- “you can probably expect to spend an hour or more working through each individual session.”
What you need
- “Campbell, N. A., J.B. Reece, et al. Biology. 8th ed. Pearson Benjamin Cummings, 2008.”
“OCW users will find equal value in most standard introductory biology textbooks.”
Books
- The free book on our Start page for this course is a companion book, not a text this course assigns.
- “Throughout the course, we suggest topics of study that can be found in any standard textbook.”
If this isn't the right fit
Pre-7.01: Getting up to Speed in Biology (RES.7-001, Summer 2019) ↗
- “Prior to taking this course, you may want to review Pre-7.01 Getting up to Speed in Biology, a self-paced course designed to help prepare students for their first college-level biology class.”
- “Go to OCW's Open Learning Library site for Pre-7.01: Getting up to Speed in Biology.”
Your first sessions
- “Problems (with solutions) and interactive concept quizzes.”
Types of Organisms, Cell Composition
Covalent Bonds, Hydrogen Bonds
Macromolecules: Lipids, Carbohydrates, Nucleic Acid
- WatchMacromolecules: Lipids, Carbohydrates, Nucleic Acid, Excerpt 1
- WatchMacromolecules: Lipids, Carbohydrates, Nucleic Acid, Excerpt 2
- CheckCheck Yourself questions (on MIT's session page) ↗
- WatchHelp session: Lipids, Carbohydrates, and Nucleic Acids Practice Problem
- PracticePractice problems (PDF) ↗
- CheckSolutions (PDF) ↗
Learn one topic
21 concept pages, one per MIT session: the clips, notes and practice for that topic. MIT solutions for 20 of 21 topics.
All 21 topics
- Types of Organisms, Cell Composition MIT solutions
- Covalent Bonds, Hydrogen Bonds MIT solutions
- Macromolecules: Lipids, Carbohydrates, Nucleic Acid MIT solutions
- Proteins, Levels of Structure, Non-Covalent Forces MIT solutions
- Biochemical Reactions, Enzymes, and ATP MIT solutions
- Glycolysis, Respiration, and Fermentation MIT solutions
- Photosynthesis MIT solutions
- DNA Structure, Classic Experiments MIT solutions
- DNA Replication MIT solutions
- Transcription, Translation MIT solutions
- Alternative Approaches to Molecular Biology MIT solutions
- Gene Regulation and the Lac Operon MIT solutions
- Mendel's Laws MIT solutions
- Linkage and Recombination, Genetic Maps MIT solutions
- Pedigrees MIT solutions
- Biochemical Genetics MIT solutions
- Development of Recombinant DNA
- Basic Mechanics of Cloning: Restriction Enzymes & Cloning Vectors MIT solutions
- Constructing and Screening a Recombinant DNA Library MIT solutions
- cDNA Libraries and Expression Libraries MIT solutions
- Agarose Gel Electrophoresis, DNA Sequencing, PCR MIT solutions
Before you start
How this course was organized
What's here, and what isn't
- This course has 42 videos, each embedded on its own MIT page, across 21 sections. They're shown in MIT's listing order within each section. A verified course-wide order is not claimed for this course.
Not included here
104 items from the source could not be safely included:
- MIT's page format for this item wasn't recognized clearly enough to place it safely. (96 items)
- Referenced in a table, but without MIT's own verified order, so it isn't used to claim a sequence. (8 items)
Units
Each unit is offered as its own lecture sequence; there is no single course-wide order across units.
Materials by section
Grouped by section, as MIT organized them. Not sequenced or ordered.
Biochemistry
17 files in this section
Types of Organisms, Cell Composition
Covalent Bonds, Hydrogen Bonds
Macromolecules: Lipids, Carbohydrates, Nucleic Acid
Proteins, Levels of Structure, Non-Covalent Forces
Biochemical Reactions, Enzymes and ATP
Respiration and Fermentation
Chemiosmotic Principle, Photosynthesis
Exam 1
Molecular Biology
13 files in this section
DNA Structure, Classic Experiments
DNA Replication
Transcription, Translation
Alternative Approaches to Molecular Biology
Gene Regulation and the Lac Operon
Exam 2
Genetics
13 items in this section
Mendel's Laws
Linkage and Recombination, Genetic Maps
Pedigrees
Biochemical Genetics
- Problems Download
- Solutions Download
- Next, watch Genny work a Complementation Problem using fruit flies as an example. Download
- Human Genetics Open ↗
Exam 3
Recombinant DNA
10 files in this section
Basic Mechanics of Cloning
Constructing and Screening a Recombinant DNA Library
cDNA Libraries and Expression Libraries
Agarose Gel Electrophoresis, DNA Sequencing, PCR
Exam 4
Resource Index
43 videos
- Agarose Gel Electrophoresis, DNA Sequencing, PCR, Excerpt 1 Open ↗
- Agarose Gel Electrophoresis, DNA Sequencing, PCR, Excerpt 2 Open ↗
- Basic Mechanisms of Cloning, Excerpt 1 Open ↗
- Basic Mechanisms of Cloning, Excerpt 2 Open ↗
- Basic Mechanisms of Cloning, Excerpt 3 Open ↗
- DNA Structure and Classic experiments, Excerpt 1 Open ↗
- DNA Structure and Classic experiments, Excerpt 2 Open ↗
- Explanation of 5' and 3', C terminus, and N terminus Open ↗
- Genetics 3 Open ↗
- Macromolecules: Lipids, Carbohydrates, Nucleic Acid, Excerpt 1 Open ↗
- Macromolecules: Lipids, Carbohydrates, Nucleic Acid, Excerpt 2 Open ↗
- Mendel's Laws, Excerpt 1 Open ↗
- Mendel's Laws, Excerpt 2 Open ↗
- Overview of Recombinant DNA, Excerpt 1 Open ↗
- Overview of Recombinant DNA, Excerpt 2 Open ↗
- Proteins, Levels of Structure, Non-Covalent Forces, Excerpt 1 Open ↗
- Proteins, Levels of Structure, Non-Covalent Forces, Excerpt 2 Open ↗
- Transcription and translation, Excerpt 1 Open ↗
- Transcription and translation, Excerpt 2 Open ↗
- Types of Organisms, Cell Composition, Excerpt 1 Open ↗
- Types of Organisms, Cell Composition, Excerpt 2 Open ↗
- Covalent Bonds, Hydrogen Bonds Open ↗
- Covalent Bonds Open ↗
- Lipids, Carbohydrates, and Nucleic Acids Practice Problem Open ↗
- Biochemical Reactions, Enzymes, and ATP Open ↗
- Glycolysis, Respiration, and Fermentation Open ↗
- Photosynthesis Open ↗
- DNA Replication Open ↗
- Transcription and Translation Open ↗
- Alternative Approaches to Molecular Biology Open ↗
- Gene Regulation Open ↗
- The lac operon Open ↗
- Linkage and Recombination, Genetic maps Open ↗
- Human Genetics Open ↗
- Pedigrees Open ↗
- Human Genetics Open ↗
- Complementation Open ↗
- Complementation (Part II) Open ↗
- Constructing and Screening a Recombinant DNA Library Open ↗
- Genomic and cDNA Libraries Open ↗
- cDNA Libraries and Expression Libraries Open ↗
- Transformation and Protein Expression Open ↗
- Polymerase Chain Reaction (PCR) Open ↗
Other materials from this course
8 lecture transcripts
- 7.012 Introduction to Biology, Fall 2004 Transcript – Lecture 8 Download
- 7.012 Introduction to Biology, Fall 2004 Transcript – Lecture 8 Download
- 7.012 Introduction to Biology, Fall 2004 Transcript – Lecture 9 Download
- 7.012 Introduction to Biology, Fall 2004 Transcript – Lecture 9 Download
- 7.012 Introduction to Biology, Fall 2004 Transcript – Lecture 9 Download
- 7.012 Introduction to Biology, Fall 2004 Transcript – Lecture 9 Download
- 7.012 Introduction to Biology, Fall 2004 Transcript – Lecture 13 Download
- 7.012 Introduction to Biology, Fall 2004 Transcript – Lecture 13 Download
78 video transcripts
- Transcript for Mendel's Laws, Excerpt 1 Download
- Transcript for Alternative Approaches to Molecular Biology Download
- Transcript for Covalent Bonds, Hydrogen Bonds Download
- Transcript for Agarose Gel Electrophoresis, DNA Sequencing, PCR, Excerpt 2 Download
- Transcript for Transformation and Protein Expression Download
- Transcript for Complementation Download
- Transcript for Constructing and Screening a Recombinant DNA Library Download
- Transcript for Covalent Bonds Download
- Transcript for Agarose Gel Electrophoresis, DNA Sequencing, PCR, Excerpt 1 Download
- Transcript for Transcription and Translation Download
- Transcript for Transcription and translation, Excerpt 1 Download
- Transcript for Proteins, Levels of Structure, Non-Covalent Forces, Excerpt 2 Download
- Transcript for Explanation of 5' and 3', C terminus, and N terminus Download
- Transcript for Genomic and cDNA Libraries Download
- Transcript for DNA Structure and Classic experiments, Excerpt 2 Download
- Transcript for Agarose Gel Electrophoresis, DNA Sequencing, PCR, Excerpt 1 Download
- Transcript for Complementation (Part II) Download
- Transcript for Basic Mechanisms of Cloning, Excerpt 3 Download
- Transcript for The lac operon Download
- Transcript for Constructing and Screening a Recombinant DNA Library Download
- Transcript for Types of Organisms, Cell Composition, Excerpt 1 Download
- Transcript for Transcription and translation, Excerpt 2 Download
- Transcript for Proteins, Levels of Structure, Non-Covalent Forces, Excerpt 1 Download
- Transcript for Overview of Recombinant DNA, Excerpt 1 Download
- Transcript for Photosynthesis Download
- Transcript for Polymerase Chain Reaction (PCR) Download
- Transcript for Basic Mechanisms of Cloning, Excerpt 1 Download
- Transcript for Biochemical Reactions, Enzymes, and ATP Download
- Transcript for cDNA Libraries and Expression Libraries Download
- Transcript for Types of Organisms, Cell Composition, Excerpt 2 Download
- Transcript for Basic Mechanisms of Cloning, Excerpt 1 Download
- Transcript for Macromolecules: Lipids, Carbohydrates, Nucleic Acid, Excerpt 1 Download
- Transcript for Macromolecules: Lipids, Carbohydrates, Nucleic Acid, Excerpt 1 Download
- Transcript for cDNA Libraries and Expression Libraries Download
- Transcript for Explanation of 5' and 3', C terminus, and N terminus Download
- Transcript for Agarose Gel Electrophoresis, DNA Sequencing, PCR, Excerpt 2 Download
- Transcript for Photosynthesis Download
- Transcript for DNA Structure and Classic experiments, Excerpt 1 Download
- Transcript for Mendel's Laws, Excerpt 2 Download
- Transcript for Glycolysis, Respiration, and Fermentation Download
- Transcript for Basic Mechanisms of Cloning, Excerpt 3 Download
- Transcript for DNA Structure and Classic experiments, Excerpt 2 Download
- Transcript for Biochemical Reactions, Enzymes, and ATP Download
- Transcript for Complementation (Part II) Download
- Transcript for Proteins, Levels of Structure, Non-Covalent Forces, Excerpt 1 Download
- Transcript for Basic Mechanisms of Cloning, Excerpt 2 Download
- Transcript for Overview of Recombinant DNA, Excerpt 2 Download
- Transcript for Types of Organisms, Cell Composition, Excerpt 1 Download
- Transcript for Pedigrees Download
- Transcript for Transcription and translation, Excerpt 2 Download
- Transcript for Mendel's Laws, Excerpt 1 Download
- Transcript for Lipids, Carbohydrates, and Nucleic Acids Practice Problem Download
- Transcript for Complementation Download
- Transcript for Pedigrees Download
- Transcript for Polymerase Chain Reaction (PCR) Download
- Transcript for Overview of Recombinant DNA, Excerpt 2 Download
- Transcript for Covalent Bonds, Hydrogen Bonds Download
- Transcript for The lac operon Download
- Transcript for Transcription and Translation Download
- Transcript for Macromolecules: Lipids, Carbohydrates, Nucleic Acid, Excerpt 2 Download
- Transcript for Linkage and Recombination, Genetic maps Download
- Transcript for Genomic and cDNA Libraries Download
- Transcript for Alternative Approaches to Molecular Biology Download
- Transcript for Overview of Recombinant DNA, Excerpt 1 Download
- Transcript for Glycolysis, Respiration, and Fermentation Download
- Transcript for Linkage and Recombination, Genetic maps Download
- Transcript for Proteins, Levels of Structure, Non-Covalent Forces, Excerpt 2 Download
- Transcript for Transcription and translation, Excerpt 1 Download
- Transcript for Transformation and Protein Expression Download
- Transcript for Covalent Bonds Download
- Transcript for Macromolecules: Lipids, Carbohydrates, Nucleic Acid, Excerpt 2 Download
- Transcript for DNA Replication Download
- Transcript for DNA Replication Download
- Transcript for DNA Structure and Classic experiments, Excerpt 1 Download
- Transcript for Types of Organisms, Cell Composition, Excerpt 2 Download
- Transcript for Basic Mechanisms of Cloning, Excerpt 2 Download
- Transcript for Mendel's Laws, Excerpt 2 Download
- Transcript for Lipids, Carbohydrates, and Nucleic Acids Practice Problem Download
39 images
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- a diagram showing a ribosome in a cell, messenger RNA, and protein synthesis Open ↗
- Michelle_Mischke.jpg Open ↗
- a diagram showing circles and squares arranged in a tree formation to represent the inheritance of… Open ↗
- Sallie_W_Chisholm.jpg Open ↗
- Hazel_Sive.jpg Open ↗
- robert_dorkin.jpg Open ↗
- an illustration of the biochemical structures and molecules in a T cell receptor Open ↗
- an image showing the steps of cloning in bacterial cells Open ↗
- genevieve_gould.jpg Open ↗
- Tyler_Jacks.jpg Open ↗
- Robert_A_Weinberg.jpg Open ↗
- Eric_Lander.jpg Open ↗
MIT OpenCourseWare, Prof. Eric Lander, Prof. Robert Weinberg, Prof. Tyler Jacks, Prof. Hazel Sive, Prof. Graham Walker, Prof. Sallie Chisholm, Dr. Michelle Mischke, 7.01SC Fundamentals of Biology, Fall 2011.
License: CC BY-NC-SA 4.0 · Edition: Fall 2011 · Open the original course on OCW ↗
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