MIT OpenCourseWare

Browse materialsMIT 20.442 · Fall 2005

Molecular Structure of Biological Materials (BE.442)

Subject: Biology

Art: Robert Hooke, Micrographia Scheme 07, 1665 · Public domain

Instructor: Prof. Shuguang Zhang
Term: Fall 2005
Level: Graduate
What's inside: 1 lecture note · 1 reading · 24 other files · 5 web pages
Materials open: MIT OCW

Start here

Start course: Lecture 1: Important Role of Water Molecule, Hydration of Amino…Find a topic

Progress is saved in this browser.

Export or import progress

About this course

Source: MIT OpenCourseWare 20.442 Molecular Structure of Biological Materials (BE.442), Fall 2005, Prof. Shuguang Zhang — original course page on ocw.mit.edu ↗. License: CC BY-NC-SA 4.0. Study order: MIT's own listing order, section by section. Taken from MIT's published course files, downloaded from ocw.mit.edu on September 23, 2026. How RedLectern is built.

Materials are grouped the way MIT organized them. A verified, course-wide order has not been established here.

Before you start

Prerequisites are not listed here. Check MIT's own syllabus for this course.

How this course was organized

What's here, and what isn't

A lecture sequence of 24 items is confirmed. It stays as organized materials rather than a full course order.

Not included here

50 items from the source could not be safely included:

MIT's page format for this item wasn't recognized clearly enough to place it safely. (50 items)

Materials by section

Grouped by section, as MIT organized them. Not sequenced or ordered.

Lecture Notes

20 files

Assignments

Probing 2-D Reaction Coordinates of Amino Acid/Surface Binding by David Appleyard. (Courtesy of David Appleyard. Used with permission.)PDF Download

Exams

Other materials from this course

chp_be_442_sap.jpgJPEG image Open ↗

MIT OpenCourseWare, Prof. Shuguang Zhang, 20.442 Molecular Structure of Biological Materials (BE.442), Fall 2005.

License: CC BY-NC-SA 4.0 · Edition: Fall 2005 · Open the original course on OCW ↗

Organized by RedLectern, independent of MIT and not endorsed by MIT.

Per-resource rights are recorded on each resource; All-Rights-Reserved items are link-only, never mirrored.

Molecular Structure of Biological Materials (BE.442)

Before you start

What's here, and what isn't

Not included here

Materials by section

Lecture Notes

Assignments

Exams

Other materials from this course

Lecture 1: Important Role of Water Molecule, Hydration of Amino Acids, Protein and Other Biological Materials

Lecture 2: Amino Acids: Their Chemical and Physical Properties Influence of Ionic Strength, pH, etc.

Lecture 3: Primary and Secondary Structures of Proteins Dihedral Angles, Peptide Bonds, Planar Structure, Relationship and Propensity of Amino Acid Sequence, Secondary Structure Ramachandran Plot

Lecture 4: Alpha-helices, 310 Helix, pi Helix, Beta-helices, etc. Variation of Helices and Their Helical Bundles, Two Strand Coiled-coils, Three or Four Strand Coiled-coils, Supercoils Various Helical Rich Protein Structure Models Alpha-helices in Biological Materials

Lecture 5: Helical Coiled-coils Two-, Three-, Four- Stranded Helical Bundles Applying Coiled-coils to Nanomaterials, Molecular Springs, Switches, etc.

Lecture 6: Beta Sheets: Antiparallel, Parallel, and Twist Beta Sheet Rich Proteins Beta Sheets in Biological Materials

Lecture 7: Practical Aspects of Single Crystal X-ray Crystallography, Part 1 X-ray Single Crystal Diffraction, Fiber Diffraction Preparation of the Samples for Diffraction Analyses

Lecture 8: NMR (Guest Lecturer: Peter Carr, MIT Media Lab)

Lecture 9: Practical Aspects of Single Crystal X-ray Crystallography, Part 2

Lecture 10: Analytical Approaches and Instrumentation (Guest Lecturer: Sotirus Koutsopoulos, Ph.D)

Lecture 11: Silk

Lecture 12: Biomineralization: Sea Creatures

Lecture 13: Biomineralization: Bones and Teeth

Lecture 14: Bioadhesives

Lecture 15: Lipids as Building Materials

Lecture 16: Polysaccharides and Oligosaccharides

Lecture 17: Francis Crick Film

Lecture 18: Molecular Structure and Self-assembly of DNA and RNA

Lecture 19: Macromolecular Interactions and Protein and Adsorption (Guest Lecturer: Larry Unsworth, Ph.D, National Institute for Nanotechnology) Crystallography (Guest lecturer: Liselotte Kaiser, MIT Center for Biomedical Engineering)

Lecture 20: DNA Molecular Machines

Lecture 21: Fluorescent Proteins

Lecture 22: Self-assembling Peptide Systems (Dr. Zhang’s Research)

Lecture 23: Self-assembling Peptide Systems (Dr. Zhang’s Research) (cont.) Applying Biomimicry to Nanotechnology (Guest Lecture by Andreas Mershin)

Lecture 24: Research in Biomaterials