MIT OpenCourseWare

Browse materialsMIT 20.441J · Fall 2009

Biomaterials-Tissue Interactions

Subjects: Biology · Engineering · Mechanical Engineering

Art: В. Флемминг, Cell division according to W. Flemming (1882), 1882 · Public domain

Instructors: Prof. Ioannis Yannas, Prof. Myron Spector
Term: Fall 2009
Level: Graduate
What's inside: 4 exams · 1 lecture note · 1 reading · 44 other files · 3 web pages
Materials open: MIT OCW

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About this course

Source: MIT OpenCourseWare 20.441J Biomaterials-Tissue Interactions, Fall 2009, Prof. Ioannis Yannas, Prof. Myron Spector — original course page on ocw.mit.edu ↗. License: CC BY-NC-SA 4.0. Study order: MIT's own listing order, section by section. Taken from MIT's published course files, downloaded from ocw.mit.edu on September 23, 2026. How RedLectern is built.

Materials are grouped the way MIT organized them. A verified, course-wide order has not been established here.

Before you start

Prerequisites are not listed here. Check MIT's own syllabus for this course.

This course’s cited books, in our reading lists: Tissue and Organ Regeneration in Adults

How this course was organized

What's here, and what isn't

MIT's own materials here did not support a verified, course-wide order, so they are grouped by section instead.

Not included here

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MIT's page format for this item wasn't recognized clearly enough to place it safely. (14 items)

Materials by section

Grouped by section, as MIT organized them. Not sequenced or ordered.

Readings

Lecture Notes

30 files

Assignments

9 files

Exams

MIT OpenCourseWare, Prof. Ioannis Yannas, Prof. Myron Spector, 20.441J Biomaterials-Tissue Interactions, Fall 2009.

License: CC BY-NC-SA 4.0 · Edition: Fall 2009 · Open the original course on OCW ↗

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Biomaterials-Tissue Interactions

Before you start

What's here, and what isn't

Not included here

Materials by section

Readings

Lecture Notes

Assignments

Exams

Lecture 1: Survey of clinical cases of biomaterials-tissue interactions

Lecture 2: Tissue structures and unit cell processes Integrins and adhesion proteins

Lecture 3: Unit cell processes comprising the healing response

Lecture 4: Unit cell processes underlying tissue engineering

Lecture 5: Structure and function of naturally occurring ECMs

Lecture 6: ECM does not regenerate spontaneously

Lecture 7: Quiz 1

Lecture 8: Analysis of surfaces of biomaterials and protein adsorption

Lecture 9: Phenotype changes following adhesion on biomaterials

Lecture 10: Structural determinants of biologically active materials

Lecture 11: Methodology for cell-surface interactions

Lecture 12: Cell-scaffold interactions during regeneration

Lecture 13: Noncooperative cell-surface interactions

Lecture 14: From randomness to cooperativity

Lecture 15: Quiz 2

Lecture 16: Tissue response to implants; biocompatibility

Lecture 17: Epithelialization (epidermal regeneration) and endothelialization of vascular prostheses

Lecture 18: In vivo synthesis of skin

Lecture 19: In vivo synthesis of peripheral nerve

Lecture 20: Rules for synthesis of tissues and organs

Lecture 21: Joints and dental tissues: prosthetic replacement

Lecture 22: Implants for bone regeneration

Lecture 23: Regeneration of soft musculoskeletal tissues

Lecture 24: Biomaterial applications in the heart and other organs

Lecture 25: Quiz 3