Calendar · Lecture Notes
MIT OpenCourseWare
Analysis of Biological Networks (BE.440)
Art: В. Флемминг, Cell division according to W. Flemming (1882), 1882 · Public domain
- Instructors
- Prof. John Essigmann, Prof. Ram Sasisekharan
- Term
- Fall 2004
- Level
- Graduate
- What's inside
- 1 lecture note · 1 reading · 15 other files · 5 web pages
- Materials open
- MIT OCW
About this course
Source: MIT OpenCourseWare 20.440 Analysis of Biological Networks (BE.440), Fall 2004, Prof. John Essigmann, Prof. Ram Sasisekharan — original course page on ocw.mit.edu ↗. License: CC BY-NC-SA 4.0. Study order: MIT's own listing order, section by section. Taken from MIT's published course files, downloaded from ocw.mit.edu on September 23, 2026. How RedLectern is built.
Materials are grouped the way MIT organized them. A verified, course-wide order has not been established here.
Before you start
Prerequisites are not listed here. Check MIT's own syllabus for this course.
How this course was organized
What's here, and what isn't
- A lecture sequence of 24 items is confirmed. No assignments or exams were found for this course, so it stays as organized materials rather than a full course order.
Not included here
31 items from the source could not be safely included:
- MIT's page format for this item wasn't recognized clearly enough to place it safely. (31 items)
Materials by section
Grouped by section, as MIT organized them. Not sequenced or ordered.
Lecture Notes
7 files
- Information flow in the reverse direction - from DNA to RNA to protein (the central dogma) Review of regulatory… Download
- Decoding Information I (Transcription Regulation) Download
- Decoding Information II (Translation) Download
- Analysis of the Interferon Network (The JAK/STAT system) Download
- Analysis of the Interferon Network Download
- Analysis of the Interferon Network (cont.) Download
- Chemotaxis I - How Salvage Pathways Supplement Core Biochemical Pathways Download
Projects
Other materials from this course
7 files
- Lecture presentation (chemotaxis_2004.pdf) Download
- Lecture presentation (lecture_01.pdf) Download
- Lecture presentation (lecture_02.pdf) Download
- Lecture presentation (mam_ep_morp_nov5.pdf) Download
- Lecture presentation (res_sys_ast_dec1.pdf) Download
- Lecture presentation (mam_ep_morp_ii.pdf) Download
- mam_epi_m_ll_bw.pdf Download
Course outline
Calendar · Lecture Notes
Lecture 2: Information flow in the reverse direction - from DNA to RNA to protein (the central dogma) Review of regulatory circuits and introduction to the concept of evolutionary genomics Key Issues: DNA replication and repair errors lead to mutations. Loss of mismatch repair leads to a hyper-Rec phenotype, which facilitates horizontal gene transfer (antibiotic resistance, etc.)
Calendar · Lecture Notes
Lecture 3: Decoding Information I (Transcription Regulation)
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Lecture 4: Modeling Macromolecular Structure I Individual Homework Assignments
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Lecture 5: Decoding Information II (Translation)
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Lecture 6: Modeling Macromolecular Structure II Students Present Homework
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Lecture 7: Roundtable Discussion
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Lecture 8: How to Write an NIH Grant Proposal
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Lecture 9: Analysis of the Interferon Network (The JAK/STAT System)
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Lecture 10: Analysis of the Interferon Network
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Lecture 11: Analysis of the Interferon Network (cont.)
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Lecture 12: Analysis of the Interferon Network (cont.)
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Lecture 13: Roundtable 1: Students Present Model Projects on Apoptosis
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Lecture 14: Chemotaxis I - How Salvage Pathways Supplement Core Biochemical Pathways The Che System Receptor Methylation as a Mechanism of Control of Chemotaxis
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Lecture 15: Chemotaxis II - How CheY(P) Signals to the Flagellar Motor Chemiosmotic Coupling Chemotaxis III. Proton Pumps
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Lecture 16: Introduction to the Extracellular Matrix Roundtable 2 Will be Delayed for a Few Weeks
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Lecture 17: Epithelial Cell Morphogenesis Signaling Hierarchy I
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Lecture 18: Epithelial Cell Morphogenesis Signaling Hierarchy II
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Lecture 19: Round Table Discussion
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Lecture 20: Epithelial Cell Morphogenesis Signaling Hierarchy III
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Lecture 21: Roundtable 3
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Lecture 22: Changes in Lung Epithelium During Pathogenesis I
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Lecture 23: Changes in Lung Epithelium During Pathogenesis II
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Lecture 24: Network Example: Functional Glycomics
MIT OpenCourseWare, Prof. John Essigmann, Prof. Ram Sasisekharan, 20.440 Analysis of Biological Networks (BE.440), Fall 2004.
License: CC BY-NC-SA 4.0 · Edition: Fall 2004 · Open the original course on OCW ↗
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