MIT OpenCourseWare

Browse materialsMIT 20.320 · Fall 2012

Analysis of Biomolecular and Cellular Systems

Subjects: Biology · Engineering

Art: Robert Hooke, Micrographia Scheme 07, 1665 · Public domain

Instructors: Prof. Ernest Fraenkel, Prof. Forest White
Term: Fall 2012
Level: Undergraduate
What's inside: 18 problem sets · 9 exams · 19 solutions · 29 lecture notes · 21 other files · 11 web pages
Materials open: MIT OCW

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About this course

Source: MIT OpenCourseWare 20.320 Analysis of Biomolecular and Cellular Systems, Fall 2012, Prof. Ernest Fraenkel, Prof. Forest White — original course page on ocw.mit.edu ↗. License: CC BY-NC-SA 4.0. Study order: MIT's own listing order, section by section. Taken from MIT's published course files, downloaded from ocw.mit.edu on September 23, 2026. How RedLectern is built.

Materials are grouped the way MIT organized them. A verified, course-wide order has not been established here.

Has MIT solutions 20 files in this course are named by MIT as solutions.

Before you start

Prerequisites are not listed here. Check MIT's own syllabus for this course.

How this course was organized

What's here, and what isn't

MIT's own materials here did not support a verified, course-wide order, so they are grouped by section instead.

Not included here

23 items from the source could not be safely included:

MIT's page format for this item wasn't recognized clearly enough to place it safely. (20 items)
Referenced in a table, but without MIT's own verified order, so it isn't used to claim a sequence. (3 items)

Materials by section

Grouped by section, as MIT organized them. Not sequenced or ordered.

Modeling of Cellular Systems

29 files in this section

10 files

Study Problems

10 problem sets

Protein Networks Project

9 files

Modeling and Manipulating Biomolecular Interactions

31 files in this section

20 files

Study Problems

Protein Design Project

Exams

9 files

Study Materials

27 files

Other materials from this course

MIT OpenCourseWare, Prof. Ernest Fraenkel, Prof. Forest White, 20.320 Analysis of Biomolecular and Cellular Systems, Fall 2012.

License: CC BY-NC-SA 4.0 · Edition: Fall 2012 · Open the original course on OCW ↗

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Analysis of Biomolecular and Cellular Systems

Before you start

What's here, and what isn't

Not included here

Materials by section

Modeling of Cellular Systems

Study Problems

Protein Networks Project

Modeling and Manipulating Biomolecular Interactions

Study Problems

Protein Design Project

Exams

Study Materials

Other materials from this course

Lecture 12: Predictive models of biology, genome editing, sensors, light-activated proteins, new enzymes, electrostatics (PDF - 1.4MB)

Lecture 13: Hydrogen bonding, the hydrophobic effect, how we represent proteins (PDF - 2.4MB)

Lecture 14: Paralogues and orthologues, protein therapeutics (PDF) (These lecture notes are incomplete.)

Lecture 15: Specificity (PDF)

Lecture 16: The metropolis algorithm (PDF)

Lecture 17: Gradient descent, molecular dynamics, ΔΔG for small molecules, pharma priorities (PDF - 1.8MB)

Lecture 18: Drug development case study: Imatinib (PDF)

Lecture 20: Guest lecture by Rebecca L. Carrier: Impact of drug delivery of effectiveness (PDF) Courtesy of Rebecca L. Carrier. Used with permission.

Lecture 21: Protein folding: thermodynamics (PDF - 1.9MB)

Lecture 22: Kinetics of folding, predicting protein structure (PDF - 2.2MB)

Lecture 23: Structure from sequence (PDF - 1.3MB)

Lecture 24: Kinases, graph theory, experimental and computational techniques (PDF - 1.3MB)